Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9QZL0 / RIPK3_MOUSE
Protein Name Receptor-interacting serine/threonine-protein kinase 3
Gene Name Name: Ripk3
Synonyms:Rip3;
Organism Mus musculus (Mouse)

PRO ID PR:Q9QZL0
DAG View
PRO Name receptor-interacting serine/threonine-protein kinase 3 (mouse)
Definition A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of mouse.
Short Label mRIPK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9QZL0 (Ripk3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus   UniProt 23612963
K5 Ubiquitination PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus   UniProt 23612963
S184 Phosphorylation PhosphoSitePlus
S204 Phosphorylation RLIMS-P 32855420
T231 Phosphorylation Q9QZL0 (Ripk3) PhosphoSitePlus   RLIMS-P   UniProt 23612963, 27819682
S232 Phosphorylation Q9QZL0 (Ripk3) PhosphoSitePlus   RLIMS-P   UniProt 23612963, 31645676, 27819682
T257 Phosphorylation PhosphoSitePlus   UniProt 23612963
K264 Ubiquitination PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus   UniProt 23612963
S326 Phosphorylation PhosphoSitePlus   UniProt 23612963
T338 Phosphorylation PhosphoSitePlus   UniProt 23612963
S353 Phosphorylation PhosphoSitePlus   UniProt 23612963
K359 Ubiquitination PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 33870135, 23612963
T374 Phosphorylation PhosphoSitePlus
T378 O-Glycosylation GlyGen 32782141
S380 Phosphorylation PhosphoSitePlus   UniProt 23612963
T392 O-Glycosylation GlyGen 32782141
T392 Phosphorylation PhosphoSitePlus   UniProt 23612963
T398 O-Glycosylation GlyGen 32782141
T399 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 22028470
K469 Ubiquitination PhosphoSitePlus
R477 Methylation PhosphoSitePlus   UniProt 24129315
R479 Methylation PhosphoSitePlus


Q9QZL0 (Ripk3) as PTM Enzyme



Substrate Site Score Source PMID
Q6PHZ2 (Camk2d) T287 PhosphoSitePlus 26726877
Q9D2Y4 (Mlkl) S345 PhosphoSitePlus 24012422
Q9D2Y4 (Mlkl) S347 PhosphoSitePlus 24012422
Q9D2Y4 (Mlkl) T349 PhosphoSitePlus 24012422
Q9QZL0 (Ripk3) T231 UniProt 23612963
Q9QZL0 (Ripk3) S232 UniProt 23612963


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9QZL0 (Ripk3) T231 Q9D2Y4 (Mlkl) unknown eFIP 23612963