iPTMnet Report for Q9P2W9 (STX18)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P2W9 / STX18_HUMAN
Protein Name Syntaxin-18
Gene Name Name: STX18
ORFNames:GIG9;
Organism Homo sapiens (Human)

PRO ID PR:Q9P2W9
DAG View
PRO Name syntaxin-18 (human)
Definition A syntaxin-18 that is encoded in the genome of human.
Short Label hSTX18
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P2W9 (STX18) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K21 Ubiquitination PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
T91 Phosphorylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S167 Phosphorylation IEDB   PhosphoSitePlus 35494241
K168 Ubiquitination PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S189 Phosphorylation HPRD   PhosphoSitePlus 19413330
S194 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
T271 Phosphorylation PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S42 N42 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K62 E62 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K147 E147 Biomuta DOID:1324 / lung cancer [ cosmic ]
T181 I181 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S248 G248 Biomuta DOID:363 / uterine cancer [ icgc ]
T271 M271 Biomuta DOID:4159 / skin cancer [ cosmic ]