iPTMnet Report for Q9P2S5 (WRAP73)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P2S5 / WRP73_HUMAN
Protein Name WD repeat-containing protein WRAP73
Gene Name Name: WRAP73
Synonyms:WDR8;
Organism Homo sapiens (Human)

PRO ID PR:Q9P2S5
DAG View
PRO Name WD repeat-containing protein WRAP73 (human)
Definition A WD repeat-containing protein WRAP73 that is encoded in the genome of human.
Short Label hWRAP73
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P2S5 (WRAP73) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K15 Ubiquitination PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
C26 Methylation IEDB 31844290
C122 Methylation IEDB 31844290
S125 Phosphorylation HPRD   PhosphoSitePlus 17322306
Y128 Phosphorylation PhosphoSitePlus
Y131 Phosphorylation HPRD   PhosphoSitePlus 17322306
K133 Ubiquitination PhosphoSitePlus
C135 Methylation IEDB 31844290
T140 Phosphorylation HPRD 17322306
Y159 Phosphorylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
C199 Methylation IEDB 31844290
S228 Phosphorylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
S281 Phosphorylation IEDB   PhosphoSitePlus   UniProt 27920218, 23186163
K307 Ubiquitination PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
C453 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y128 C128 Biomuta DOID:1319 / brain cancer [ cosmic ]
C135 Y135 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T140 I140 Biomuta DOID:4159 / skin cancer [ cosmic ]
S228 Y228 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S228 P228 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S228 F228 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K307 T307 Biomuta DOID:3571 / liver cancer [ cosmic ]
C453 F453 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]