iPTMnet Report for Q9P2R6 (RERE)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P2R6 / RERE_HUMAN
Protein Name Arginine-glutamic acid dipeptide repeats protein
Gene Name Name: RERE
Synonyms:ARG,ARP,ATN1L,KIAA0458;
Organism Homo sapiens (Human)

PRO ID PR:Q9P2R6
DAG View
PRO Name arginine-glutamic acid dipeptide repeats protein (human)
Definition An arginine-glutamic acid dipeptide repeats protein that is encoded in the genome of human.
Short Label hRERE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P2R6 (RERE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation PhosphoSitePlus
S53 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S56 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
T120 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y122 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
Y268 Phosphorylation PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
S304 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 24275569, 18220336
T309 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
T349 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
T466 Phosphorylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
T473 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
S577 O-Glycosylation GlyGen 30379171, 34019948, 29351928, ...35132862, 35254053
S577 Phosphorylation PhosphoSitePlus
R578 Methylation PhosphoSitePlus
S580 O-Glycosylation GlyGen 30379171
S580 Phosphorylation PhosphoSitePlus
S582 O-Glycosylation GlyGen 30379171
T583 O-Glycosylation GlyGen 30379171
S594 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
T599 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S600 Phosphorylation PhosphoSitePlus   UniProt 23186163
S609 Phosphorylation PhosphoSitePlus
S613 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 24275569
S615 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
T619 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
K635 Acetylation PhosphoSitePlus
K637 Sumoylation PhosphoSitePlus
S641 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S642 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 20068231
K645 Acetylation PhosphoSitePlus
S656 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 15302935, 18669648
T671 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 19690332
S679 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 19690332
S681 Phosphorylation PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
S955 Phosphorylation PhosphoSitePlus
S1106 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 24275569, ...18220336
S1113 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 24275569, 18220336
S1115 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T1119 Phosphorylation PhosphoSitePlus   UniProt 24275569
K1135 Ubiquitination PhosphoSitePlus
Y1150 Phosphorylation PhosphoSitePlus
S1157 Phosphorylation PhosphoSitePlus
K1158 Acetylation PhosphoSitePlus
S1231 O-Glycosylation GlyGen 30379171, 34019948, 29351928, ...35132862, 35254053
T1237 O-Glycosylation GlyGen 30379171, 34019948, 29351928, ...35132862, 35254053
T1238 O-Glycosylation GlyGen 30379171, 34019948, 29351928, ...35132862, 35254053
Y1259 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1266 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1268 Phosphorylation PhosphoSitePlus
Y1287 Phosphorylation PhosphoSitePlus
K1324 Ubiquitination PhosphoSitePlus
R1387 Methylation PhosphoSitePlus
R1395 Methylation PhosphoSitePlus
R1400 Methylation PhosphoSitePlus
R1405 Methylation PhosphoSitePlus
R1416 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S53 Phosphorylation HPRD 18669648, 18452278
S56 Phosphorylation HPRD 18669648, 18452278
S475 Phosphorylation HPRD 17081983
S486 Phosphorylation HPRD 17081983
S487 Phosphorylation HPRD 17081983
S489 Phosphorylation HPRD 17081983
S495 Phosphorylation HPRD 17081983
S498 Phosphorylation HPRD 17081983
S594 Phosphorylation HPRD 19651622, 17081983, 20068231
T599 Phosphorylation HPRD 19651622, 17081983, 20068231
S600 Phosphorylation HPRD 19651622
S613 Phosphorylation HPRD 15302935
S641 Phosphorylation HPRD 18669648, 20068231
S642 Phosphorylation HPRD 18669648, 20068231
S656 Phosphorylation HPRD 19651622, 18669648, 15302935
S679 Phosphorylation HPRD 19664995
S1106 Phosphorylation HPRD 18452278
S1113 Phosphorylation HPRD 17081983
S1115 Phosphorylation HPRD 17081983
T1119 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation HPRD 19651622, 17081983, 20068231
T45 Phosphorylation HPRD 19651622, 17081983, 20068231
S46 Phosphorylation HPRD 19651622
S87 Phosphorylation HPRD 18669648, 20068231
S88 Phosphorylation HPRD 18669648, 20068231
S102 Phosphorylation HPRD 19651622, 18669648
S125 Phosphorylation HPRD 19664995
S552 Phosphorylation HPRD 18452278
S559 Phosphorylation HPRD 17081983
S561 Phosphorylation HPRD 17081983
T565 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S46 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y122 C122 Biomuta DOID:1324 / lung cancer [ cosmic ]
S125 L125 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K223 N223 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S348 F348 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S357 F357 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S486 G486 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S580 L580 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S582 W582 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S600 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S609 G609 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S609 T609 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S621 G621 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T671 M671 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S679 L679 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S681 P681 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1266 L1266 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1287 C1287 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
R1400 H1400 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
R1400 C1400 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R1405 C1405 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ icgc ]