iPTMnet Report for Q9P2N7 (KLHL13)
Protein Information
| UniProt AC / UniProt ID | Q9P2N7 / KLH13_HUMAN |
| Protein Name | Kelch-like protein 13 |
| Gene Name | Name: KLHL13 Synonyms:BKLHD2,KIAA1309; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9P2N7 |
| PRO Name | kelch-like protein 13 (human) |
| Definition | A kelch-like protein 13 that is encoded in the genome of human. |
| Short Label | hKLHL13 |
| Category | organism-gene |
Q9P2N7 (KLHL13) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S46 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S55 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K213 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K357 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K365 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K370 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y400 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T402 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K405 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K420 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T432 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K618 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T635 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S46 | P46 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S50 | N50 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S55 | L55 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| K618 | R618 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View