iPTMnet Report for Q9P2N5 (RBM27)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P2N5 / RBM27_HUMAN
Protein Name RNA-binding protein 27
Gene Name Name: RBM27
Synonyms:KIAA1311;
Organism Homo sapiens (Human)

PRO ID PR:Q9P2N5
DAG View
PRO Name RNA-binding protein 27 (human)
Definition An RNA-binding protein 27 that is encoded in the genome of human.
Short Label hRBM27
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P2N5 (RBM27) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K59 Ubiquitination PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
Y77 Phosphorylation PhosphoSitePlus
K85 Sumoylation PhosphoSitePlus
K99 Sumoylation PhosphoSitePlus
Y118 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
K142 Acetylation PhosphoSitePlus
Y146 Phosphorylation PhosphoSitePlus
R148 Methylation PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
S183 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 34725712, 35132862, 30620550, 34019948, 31492838, 35289036
S187 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 34725712, 35132862, 30620550, 34019948, 31492838, 35289036
S187 Phosphorylation PhosphoSitePlus
R382 Methylation IEDB 28314751
T386 O-Glycosylation GlyGen   IEDB 26280087, 28314751, 32938750
S388 Phosphorylation PhosphoSitePlus
S407 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 34725712, 35132862, 30059200, 34019948, 31492838, 35289036, 30620550
T410 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 34725712, 35132862, 30620550, 34019948, 31492838, 35289036
R411 Methylation PhosphoSitePlus
R427 Methylation PhosphoSitePlus
S432 O-Glycosylation GlyGen 32574038
R433 Methylation PhosphoSitePlus
R442 Methylation PhosphoSitePlus
T447 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18220336, ...18669648, 24275569, 20068231
R455 Methylation PhosphoSitePlus   UniProt 24129315
T471 Phosphorylation phospho.ELM 18669648
S472 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
T477 Phosphorylation PhosphoSitePlus
T497 O-Glycosylation GlyGen 32938750
R505 Methylation PhosphoSitePlus
T511 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 34725712, 35132862, 30620550, 34019948, 31492838, 35289036, 29351928
T513 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 34725712, 35132862, 30620550, 34019948, 31492838, 35289036
T513 Phosphorylation PhosphoSitePlus
T522 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 29351928, 34725712, 34019948, 30059200, 35132862, 31492838, 35289036, 30620550, 31373491
S523 O-Glycosylation GlyGen 34846842, 33214551, 32938750, ...35138101, 30379171, 29351928, 34725712, 34019948, 30059200, 35132862, 31492838, 35289036, 30620550, 31373491
T539 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 34725712, 35132862, 30620550, 34019948, 31492838, 35289036, 22661428
S546 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 33214551, 35138101, ...34846842, 30379171, 34725712, 35132862, 30059200, 34019948, 30620550, 31492838, 35289036, 29351928, 20068230
S549 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 34725712, 35132862, 30620550, 34019948, 31492838, 35289036, 29351928
T552 O-Glycosylation GlyGen 34846842, 33214551, 35138101, ...30379171, 34725712, 35132862, 30620550, 34019948, 31492838, 35289036, 29351928
K562 Ubiquitination PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
T647 Phosphorylation PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
T658 Phosphorylation PhosphoSitePlus
S683 O-Glycosylation GlyGen 30059200
K734 Acetylation PhosphoSitePlus
K734 Methylation PhosphoSitePlus
T737 O-Glycosylation GlyGen 30059200
S738 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 33214551, 35138101, ...34846842, 30379171, 32574038, 34725712, 35132862, 30059200, 34019948, 31492838, 35289036, 30620550, 29237092, 20068230
Y741 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus
S769 Phosphorylation PhosphoSitePlus
T781 Phosphorylation PhosphoSitePlus
K786 Ubiquitination PhosphoSitePlus
Y789 Phosphorylation PhosphoSitePlus
S790 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
S792 Phosphorylation PhosphoSitePlus
T796 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
S798 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
K799 Acetylation PhosphoSitePlus
S802 Phosphorylation PhosphoSitePlus
K814 Methylation PhosphoSitePlus
K815 Methylation PhosphoSitePlus
K850 Acetylation PhosphoSitePlus
K852 Acetylation PhosphoSitePlus
S883 Phosphorylation PhosphoSitePlus
S884 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S887 Phosphorylation PhosphoSitePlus
T888 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K900 Ubiquitination PhosphoSitePlus
K911 Ubiquitination PhosphoSitePlus
S914 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S915 Phosphorylation PhosphoSitePlus
K925 Ubiquitination PhosphoSitePlus
S927 Phosphorylation PhosphoSitePlus
R935 Methylation PhosphoSitePlus
R943 Methylation PhosphoSitePlus
K945 Methylation PhosphoSitePlus
R963 Methylation PhosphoSitePlus
K988 Ubiquitination PhosphoSitePlus
S996 O-Glycosylation GlyGen 30059200
K1003 Ubiquitination PhosphoSitePlus
S1012 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1020 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T1023 Phosphorylation phospho.ELM 18669648
K1031 Sumoylation PhosphoSitePlus
T1037 Phosphorylation PhosphoSitePlus
Y1053 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K85 M85 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K142 I142 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y146 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
R148 Q148 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y150 N150 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R427 * Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R433 H433 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R433 C433 Biomuta DOID:1319 / brain cancer [ cosmic ]
R442 Q442 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R455 C455 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S472 L472 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S474 C474 Biomuta DOID:363 / uterine cancer [ cosmic ]
T477 I477 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T513 S513 Biomuta DOID:1324 / lung cancer [ cosmic ]
S523 F523 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S546 L546 Biomuta DOID:4159 / skin cancer [ cosmic ]
K562 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K562 T562 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S566 G566 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S738 A738 Biomuta DOID:1319 / brain cancer [ icgc ]
S769 C769 Biomuta DOID:1324 / lung cancer [ cosmic ]
S798 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K850 Q850 Biomuta DOID:4362 / cervical cancer [ icgc ]
R943 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R963 G963 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1003 T1003 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1012 * Biomuta [ cosmic ]
S1012 A1012 Biomuta DOID:9256 / colorectal cancer [ cosmic ]