Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P2K3 / RCOR3_HUMAN
Protein Name REST corepressor 3
Gene Name Name: RCOR3
Synonyms:KIAA1343;
Organism Homo sapiens (Human)

PRO ID PR:Q9P2K3
DAG View
PRO Name REST corepressor 3 (human)
Definition A REST corepressor 3 that is encoded in the genome of human.
Short Label hRCOR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P2K3 (RCOR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K20 Ubiquitination PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
Y46 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S156 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983
T163 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus   UniProt 23186163
K193 Ubiquitination PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
T376 Phosphorylation PhosphoSitePlus   UniProt 23186163
T384 Phosphorylation PhosphoSitePlus
R440 Methylation PhosphoSitePlus
R445 Methylation PhosphoSitePlus   UniProt 24129315
R457 Methylation PhosphoSitePlus   UniProt 24129315
Site PTM Type PTM Enzyme Score Source PMID
S156 Phosphorylation HPRD 17081983, 20068231
T163 Phosphorylation HPRD 17081983
S171 Phosphorylation HPRD 17081983, 20068231
Y173 Phosphorylation HPRD 17081983
S372 Phosphorylation HPRD 18452278
S375 Phosphorylation HPRD 18452278
T376 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
T430 Phosphorylation PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K20 N20 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:1115 / sarcoma [ tcga ]
K51 M51 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S171 C171 Biomuta DOID:263 / kidney cancer [ cosmic ]
S232 F232 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S375 R375 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R440 W440 Biomuta DOID:1319 / brain cancer [ icgc ]
R457 H457 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]