iPTMnet Report for Q9P2K2 (TXNDC16)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P2K2 / TXD16_HUMAN
Protein Name Thioredoxin domain-containing protein 16 precursor
Gene Name Name: TXNDC16
Synonyms:ERP90;
Organism Homo sapiens (Human)

PRO ID PR:Q9P2K2
DAG View
PRO Name thioredoxin domain-containing protein 16 (human)
Definition A thioredoxin domain-containing protein 16 that is encoded in the genome of human.
Short Label hTXNDC16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P2K2 (TXNDC16) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y75 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
C84 Methylation IEDB 31844290
K86 Ubiquitination PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
T236 Phosphorylation PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
T246 Phosphorylation PhosphoSitePlus
N460 N-Glycosylation GlyGen 24190977
Y524 Phosphorylation PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
Y572 Phosphorylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
T794 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S78 L78 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic ]
Y572 C572 Biomuta DOID:1319 / brain cancer [ icgc ]
T794 A794 Biomuta DOID:1324 / lung cancer [ cosmic ]