iPTMnet Report for Q9P2E9 (RRBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P2E9 / RRBP1_HUMAN
Protein Name Ribosome-binding protein 1
Gene Name Name: RRBP1
Synonyms:KIAA1398;
Organism Homo sapiens (Human)

PRO ID PR:Q9P2E9
DAG View
PRO Name ribosome-binding protein 1 (human)
Definition A ribosome-binding protein 1 that is encoded in the genome of human.
Short Label hRRBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P2E9 (RRBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K47 Ubiquitination PhosphoSitePlus
K51 Methylation PhosphoSitePlus
T52 Phosphorylation IEDB 35494241
T110 Phosphorylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
K166 Acetylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K175 Acetylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
T191 Phosphorylation PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
T225 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
T235 Phosphorylation PhosphoSitePlus   UniProt 20068231
K241 Ubiquitination PhosphoSitePlus
T245 Phosphorylation PhosphoSitePlus   UniProt 17081983, 20068231
K251 Ubiquitination PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus   UniProt 17081983, 20068231
K261 Ubiquitination PhosphoSitePlus
K270 Acetylation PhosphoSitePlus
T274 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T275 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T287 Phosphorylation PhosphoSitePlus
K310 Acetylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K320 Acetylation PhosphoSitePlus
K330 Acetylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K340 Acetylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K350 Acetylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
K360 Acetylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
K370 Acetylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K380 Acetylation PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
K390 Acetylation PhosphoSitePlus
K400 Acetylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K410 Acetylation PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus
K420 Acetylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K430 Acetylation PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
K440 Acetylation PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K450 Acetylation PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
K460 Acetylation PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
K470 Acetylation PhosphoSitePlus
K480 Acetylation PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
K490 Acetylation PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
K500 Acetylation PhosphoSitePlus
K520 Acetylation PhosphoSitePlus
S533 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
S552 Phosphorylation PhosphoSitePlus
K568 Ubiquitination PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus   UniProt 24275569
S575 Phosphorylation PhosphoSitePlus
S583 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 15302935, 17081983
T600 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus
S615 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...16964243, 15302935, 18669648, 24275569, 17924679, 20068231, 17081983
K620 Sumoylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus
T684 Phosphorylation PhosphoSitePlus
K687 Ubiquitination PhosphoSitePlus
T689 Phosphorylation PhosphoSitePlus
K699 Methylation PhosphoSitePlus
K699 Ubiquitination PhosphoSitePlus
T711 Phosphorylation PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
T793 Phosphorylation PhosphoSitePlus
S803 Phosphorylation PhosphoSitePlus
T813 Phosphorylation PhosphoSitePlus
S814 Phosphorylation PhosphoSitePlus
S818 Phosphorylation PhosphoSitePlus
K819 Ubiquitination PhosphoSitePlus
C892 S-Nitrosylation dbSNO 20140087
S896 Phosphorylation PhosphoSitePlus
S900 Phosphorylation PhosphoSitePlus   UniProt 24275569
K921 Ubiquitination PhosphoSitePlus
S924 Phosphorylation PhosphoSitePlus
S951 Phosphorylation PhosphoSitePlus
T954 Phosphorylation PhosphoSitePlus
S959 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S978 Phosphorylation PhosphoSitePlus   UniProt 21406692
K990 Ubiquitination PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus
K1001 Ubiquitination PhosphoSitePlus
K1026 Ubiquitination PhosphoSitePlus
K1092 Ubiquitination PhosphoSitePlus
K1098 Ubiquitination PhosphoSitePlus
S1108 Phosphorylation PhosphoSitePlus
S1112 Phosphorylation PhosphoSitePlus
K1113 Ubiquitination PhosphoSitePlus
C1128 S-Nitrosylation dbSNO 26338901
K1147 Ubiquitination PhosphoSitePlus
K1169 Ubiquitination PhosphoSitePlus
K1175 Ubiquitination PhosphoSitePlus
C1216 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
K1241 Ubiquitination PhosphoSitePlus
K1246 Ubiquitination PhosphoSitePlus
K1262 Ubiquitination PhosphoSitePlus
S1276 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1277 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 24275569
C1323 S-Nitrosylation dbSNO 20140087
T1334 O-Glycosylation GlyGen 25813380
S1341 Phosphorylation PhosphoSitePlus
K1350 Ubiquitination PhosphoSitePlus
K1358 Acetylation PhosphoSitePlus
S1402 Phosphorylation PhosphoSitePlus
S1403 Phosphorylation PhosphoSitePlus
S1409 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S135 Phosphorylation HPRD 20068231
S185 Phosphorylation HPRD 18691976, 16964243, 15302935, ...19664994, 19691289, 19664995, 19651622, 18669648, 20166139, 19007248, 18452278, 17924679, 20068231, 17081983
T360 Phosphorylation HPRD 20068231
S526 Phosphorylation HPRD 20166139
S830 Phosphorylation HPRD 20068231
S843 Phosphorylation HPRD 20166139, 18669648, 17081983, ...20068231
S844 Phosphorylation HPRD 18578522, 17081983, 18452278, ...18669648, 20166139, 19415658, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S185 I185 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T191 S191 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T225 I225 Biomuta DOID:4159 / skin cancer [ cosmic ]
T274 A274 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K310 I310 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K311 R311 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K351 E351 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K370 R370 Biomuta DOID:10283 / prostate cancer [ icgc ]
K410 R410 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K420 E420 Biomuta DOID:3571 / liver cancer [ cosmic ]
K430 R430 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K440 R440 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
K441 R441 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K450 R450 Biomuta [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] DOID:1725 / peritoneum cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
K460 R460 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
K470 R470 Biomuta DOID:4362 / cervical cancer [ icgc ]
K500 R500 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K500 Q500 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S533 T533 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S552 L552 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S573 A573 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T600 A600 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T610 A610 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T610 R610 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S615 I615 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S843 F843 Biomuta DOID:4159 / skin cancer [ cosmic ]
S951 F951 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1112 F1112 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1112 T1112 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1276 F1276 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1358 E1358 Biomuta DOID:1324 / lung cancer [ cosmic ]