iPTMnet Report for Q9P289 (STK26)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P289 / STK26_HUMAN
Protein Name Serine/threonine-protein kinase 26
Gene Name Name: STK26
Synonyms:MASK;
Organism Homo sapiens (Human)

PRO ID PR:Q9P289
DAG View
PRO Name serine/threonine-protein kinase 26 (human)
Definition A serine/threonine-protein kinase 26 that is encoded in the genome of human.
Short Label hSTK26
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P289 (STK26) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19369195, 21406692, 20068231
S4 Phosphorylation PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...19369195, 20068231
K32 Ubiquitination PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
Y101 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus
T172 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
T178 Phosphorylation P17612 (PRKACA) , Q9P289 (STK26) PhosphoSitePlus   RLIMS-P   UniProt 18691976, 23186163, 19369195, ...26405038, 15037601, 19690332, 20730082
T182 Phosphorylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K233 Sumoylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
Y283 Phosphorylation PhosphoSitePlus
R290 Methylation PhosphoSitePlus
S300 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19369195, 18669648, 21406692
S304 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S306 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S309 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T320 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus   UniProt 23186163
T327 Phosphorylation PhosphoSitePlus   UniProt 23186163
T328 Phosphorylation PhosphoSitePlus   UniProt 23186163
K383 Ubiquitination PhosphoSitePlus
C392 Methylation IEDB 31844290
C392 S-Nitrosylation dbSNO 26338901
K398 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 19651622, 18691976, 20068231
T172 Phosphorylation HPRD 18767875
T178 Phosphorylation HPRD 19651622, 18691976, 15037601
S300 Phosphorylation HPRD 19651622, 18669648, 20068231
S304 Phosphorylation HPRD 19651622, 18669648, 20068231
S306 Phosphorylation HPRD 19651622, 18669648, 20068231
S309 Phosphorylation HPRD 19651622, 18669648, 20068231
T327 Phosphorylation HPRD 18691976
Site PTM Type PTM Enzyme Score Source PMID
T95 Phosphorylation HPRD 18767875
T101 Phosphorylation HPRD 19651622, 18691976, 15037601
S223 Phosphorylation HPRD 19651622, 18669648, 20068231
S227 Phosphorylation HPRD 19651622, 18669648, 20068231
S229 Phosphorylation HPRD 19651622, 18669648, 20068231
S232 Phosphorylation HPRD 19651622, 18669648, 20068231
T250 Phosphorylation HPRD 18691976
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 19651622, 18691976, 20068231
T172 Phosphorylation HPRD 18767875
T178 Phosphorylation HPRD 19651622, 18691976, 15037601
S238 Phosphorylation HPRD 19651622, 18669648, 20068231
S242 Phosphorylation HPRD 19651622, 18669648, 20068231
S244 Phosphorylation HPRD 19651622, 18669648, 20068231
S247 Phosphorylation HPRD 19651622, 18669648, 20068231
T265 Phosphorylation HPRD 18691976


Q9P289 (STK26) as PTM Enzyme



Substrate Site Score Source PMID
P15311 (EZR) T567 PhosphoSitePlus   Signor 19386264, 26405038
Q8TAE6 (PPP1R14C) T73 PhosphoSitePlus 25531779
Q8TDY4 (ASAP3) T545 Signor 28808054
Q9BUL8 (PDCD10) S39 PhosphoSitePlus 19370760
Q9BUL8 (PDCD10) T43 PhosphoSitePlus 19370760
Q9P289 (STK26) T178 UniProt 15037601


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S34 * Biomuta DOID:363 / uterine cancer [ cosmic ]
K91 N91 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K139 N139 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S227 C227 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S229 F229 Biomuta DOID:4159 / skin cancer [ cosmic ]
K233 Q233 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S242 C242 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S244 F244 Biomuta DOID:4159 / skin cancer [ cosmic ]
R290 C290 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S304 C304 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S306 F306 Biomuta DOID:4159 / skin cancer [ cosmic ]
K398 Q398 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K401 N401 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]