iPTMnet Report for Q9P287 (BCCIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P287 / BCCIP_HUMAN
Protein Name BRCA2 and CDKN1A-interacting protein
Gene Name Name: BCCIP
Synonyms:TOK1;
Organism Homo sapiens (Human)

PRO ID PR:Q9P287
DAG View
PRO Name BRCA2 and CDKN1A-interacting protein (human)
Definition A BRCA2 and CDKN1A-interacting protein that is encoded in the genome of human.
Short Label hBCCIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P287 (BCCIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R7 Methylation PhosphoSitePlus
R8 Methylation PhosphoSitePlus
S12 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S42 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231
K76 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
S112 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
S115 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K137 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
T209 O-Glycosylation GlyGen 23301498, 31492838, 28510447, ...33214551, 34019948
K211 Ubiquitination PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
K235 Acetylation PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation HPRD 17287340
S42 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
T109 Phosphorylation HPRD 20068231
S112 Phosphorylation HPRD 17081983, 20068231
S115 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation HPRD 17287340
S42 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
T109 Phosphorylation HPRD 20068231
S112 Phosphorylation HPRD 17081983, 20068231
S115 Phosphorylation HPRD 17081983
K243 Ubiquitination PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
R273 Methylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation HPRD 17287340
S42 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
T109 Phosphorylation HPRD 20068231
S112 Phosphorylation HPRD 17081983, 20068231
S115 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R7 G7 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R8 L8 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc, cosmic, icgc ] DOID:3953 / adrenal gland cancer [ cosmic, cosmic ] DOID:11934 / head and neck cancer [ icgc, icgc, icgc ] DOID:8618 / oral cavity cancer [ cosmic, cosmic, cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic, cosmic ]
T109 A109 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T109 M109 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S112 L112 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
S115 R115 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
K159 N159 Biomuta DOID:363 / uterine cancer [ icgc ]
S234 P234 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T288 S288 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T288 M288 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]