iPTMnet Report for Q9P270 (SLAIN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P270 / SLAI2_HUMAN
Protein Name SLAIN motif-containing protein 2
Gene Name Name: SLAIN2
Synonyms:KIAA1458;
Organism Homo sapiens (Human)

PRO ID PR:Q9P270
DAG View
PRO Name SLAIN motif-containing protein 2 (human)
Definition A SLAIN motif-containing protein 2 that is encoded in the genome of human.
Short Label hSLAIN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P270 (SLAIN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378
S35 Phosphorylation PhosphoSitePlus
S43 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 16964243
S48 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 16964243, ...18847512, 19664995, 18669648, 24275569
S48 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
R51 Methylation PhosphoSitePlus
S55 Phosphorylation HPRD   PhosphoSitePlus 18669648, 16964243, 20068231
S58 Phosphorylation HPRD   PhosphoSitePlus 20068231
S59 O-Glycosylation GlyGen 23301498, 30379171, 31492838, ...34019948
S59 Phosphorylation HPRD   PhosphoSitePlus 20068231
S63 O-Glycosylation GlyGen 23301498, 30379171, 31492838, ...34019948
S63 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...24275569, 20068231
R65 Methylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
T86 Phosphorylation PhosphoSitePlus
S87 Phosphorylation HPRD   PhosphoSitePlus 18669648
S88 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus   UniProt 23186163
T140 Phosphorylation PhosphoSitePlus
K144 Acetylation PhosphoSitePlus
S145 Phosphorylation HPRD   PhosphoSitePlus 20068231
S147 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 16964243, 19664994, ...18669648, 20068231
S160 Phosphorylation HPRD   PhosphoSitePlus   UniProt 16964243
T177 Phosphorylation PhosphoSitePlus
S179 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163
K182 Methylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
S234 Phosphorylation HPRD   PhosphoSitePlus 20068231
S247 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163
S250 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648
S251 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648
S254 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648
S257 Phosphorylation HPRD   PhosphoSitePlus 18669648
Y293 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
T309 Phosphorylation PhosphoSitePlus
T313 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18452278
S315 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...18452278
S323 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163
Y336 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
Y373 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
S377 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S383 Phosphorylation PhosphoSitePlus
S391 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163, 24275569, ...20068231
T397 Phosphorylation PhosphoSitePlus
S413 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 20068231
S418 Phosphorylation HPRD 17081983
S433 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S435 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
S456 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163
K459 Acetylation PhosphoSitePlus
S462 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S467 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
R472 Methylation PhosphoSitePlus
R538 Methylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
R551 Methylation PhosphoSitePlus   UniProt 24129315
K553 Methylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
Y581 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R65 G65 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S88 I88 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S145 L145 Biomuta DOID:363 / uterine cancer [ icgc ]
S147 R147 Biomuta DOID:1324 / lung cancer [ cosmic ]
S160 R160 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K182 N182 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S247 I247 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y293 F293 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T313 N313 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T313 A313 Biomuta DOID:1324 / lung cancer [ cosmic ]
S349 L349 Biomuta [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S353 L353 Biomuta DOID:3571 / liver cancer [ cosmic ]
S361 L361 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
S377 F377 Biomuta DOID:4159 / skin cancer [ cosmic ]
S391 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R472 W472 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ icgc ]
R472 Q472 Biomuta DOID:1324 / lung cancer [ cosmic ]
R538 I538 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R551 C551 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R551 H551 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y581 H581 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]