Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P267 / MBD5_HUMAN
Protein Name Methyl-CpG-binding domain protein 5
Gene Name Name: MBD5
Synonyms:KIAA1461;
Organism Homo sapiens (Human)

PRO ID PR:Q9P267
DAG View
PRO Name methyl-CpG-binding domain protein 5 (human)
Definition A methyl-CpG-binding domain protein 5 that is encoded in the genome of human.
Short Label hMBD5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P267 (MBD5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S205 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
T305 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus
T432 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
S530 O-Glycosylation GlyGen 34019948, 35254053
T1283 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S238 Y238 Biomuta DOID:363 / uterine cancer [ icgc ]
S263 Y263 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T302 A302 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
S431 L431 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S456 L456 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S530 G530 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1283 N1283 Biomuta DOID:363 / uterine cancer [ icgc ]