iPTMnet Report for Q9P253 (VPS18)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P253 / VPS18_HUMAN
Protein Name Vacuolar protein sorting-associated protein 18 homolog
Gene Name Name: VPS18
Synonyms:KIAA1475;
Organism Homo sapiens (Human)

PRO ID PR:Q9P253
DAG View
PRO Name vacuolar protein sorting-associated protein 18 homolog (human)
Definition A vacuolar protein sorting-associated protein 18 that is encoded in the genome of human.
Short Label hVPS18
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P253 (VPS18) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
S3 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y8 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus   UniProt 23186163
S13 Phosphorylation PhosphoSitePlus   UniProt 23186163
R14 Methylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K362 Acetylation PhosphoSitePlus   UniProt 19608861
K367 Ubiquitination PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
C445 Methylation IEDB 31844290
K476 Ubiquitination PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
S528 Phosphorylation HPRD 17081983
S529 Phosphorylation HPRD 17081983
K597 Ubiquitination PhosphoSitePlus
S689 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648
Y717 Phosphorylation PhosphoSitePlus
K758 Ubiquitination PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
S829 Phosphorylation PhosphoSitePlus
C856 Methylation IEDB 31844290
K901 Ubiquitination PhosphoSitePlus
K910 Ubiquitination PhosphoSitePlus
S912 Phosphorylation PhosphoSitePlus   UniProt 23186163
K916 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 T3 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S30 L30 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K362 T362 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K362 N362 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S479 G479 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S529 T529 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]