iPTMnet Report for Q9P246 (STIM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P246 / STIM2_HUMAN
Protein Name Stromal interaction molecule 2 precursor
Gene Name Name: STIM2
Synonyms:KIAA1482;
Organism Homo sapiens (Human)

PRO ID PR:Q9P246
DAG View
PRO Name stromal interaction molecule 2 (human)
Definition A stromal interaction molecule 2 that is encoded in the genome of human.
Short Label hSTIM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P246 (STIM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K164 Ubiquitination PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
Y320 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
S463 Phosphorylation PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus   UniProt 23186163
S539 Phosphorylation PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
Y581 Phosphorylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
S609 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S613 Phosphorylation PhosphoSitePlus
Y617 Phosphorylation PhosphoSitePlus
T619 Phosphorylation PhosphoSitePlus
S621 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S626 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
S661 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S665 Phosphorylation PhosphoSitePlus   UniProt 23186163
S668 Phosphorylation PhosphoSitePlus
S678 Phosphorylation PhosphoSitePlus
S680 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S697 Phosphorylation PhosphoSitePlus   UniProt 24275569
C698 S-Nitrosylation dbSNO 26338901
S699 Phosphorylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus
K742 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S518 G518 Biomuta DOID:363 / uterine cancer [ icgc ]
S583 F583 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S626 L626 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S640 L640 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S678 Y678 Biomuta DOID:263 / kidney cancer [ cosmic ]
S699 A699 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K742 R742 Biomuta DOID:4159 / skin cancer [ cosmic ]