iPTMnet Report for Q9P242 (NYAP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P242 / NYAP2_HUMAN
Protein Name Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2
Gene Name Name: NYAP2
Synonyms:KIAA1486;
Organism Homo sapiens (Human)

PRO ID PR:Q9P242
DAG View
PRO Name neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 (human)
Definition A neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 that is encoded in the genome of human.
Short Label hNYAP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P242 (NYAP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y31 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
T205 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
Y268 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
T356 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus   UniProt 18669648
T435 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
T447 Phosphorylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
S462 O-Glycosylation GlyGen 30059200
S462 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S468 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
T476 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
T494 Phosphorylation PhosphoSitePlus
Y495 Phosphorylation PhosphoSitePlus
T506 Phosphorylation PhosphoSitePlus
T508 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
T623 Phosphorylation PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
T632 Phosphorylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y31 C31 Biomuta DOID:263 / kidney cancer [ cosmic ]
S111 T111 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S111 Y111 Biomuta DOID:4159 / skin cancer [ cosmic ]
T169 I169 Biomuta DOID:3571 / liver cancer [ cosmic ]
S206 Y206 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y245 H245 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S294 L294 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T298 I298 Biomuta DOID:3571 / liver cancer [ cosmic ]
S379 L379 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S413 L413 Biomuta DOID:4159 / skin cancer [ cosmic ]
S413 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S425 Y425 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S462 L462 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S468 R468 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S471 A471 Biomuta DOID:4159 / skin cancer [ cosmic ]
S471 L471 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S481 A481 Biomuta DOID:4159 / skin cancer [ cosmic ]
S481 L481 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y495 N495 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S528 L528 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S530 I530 Biomuta DOID:1324 / lung cancer [ cosmic ]
T623 M623 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T623 K623 Biomuta DOID:4159 / skin cancer [ cosmic ]
S630 L630 Biomuta DOID:4159 / skin cancer [ cosmic ]
S647 L647 Biomuta DOID:4159 / skin cancer [ cosmic ]