Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P227 / RHG23_HUMAN
Protein Name Rho GTPase-activating protein 23
Gene Name Name: ARHGAP23
Synonyms:KIAA1501;
Organism Homo sapiens (Human)

PRO ID PR:Q9P227
DAG View
PRO Name Rho GTPase-activating protein 23 (human)
Definition A Rho GTPase-activating protein 23 that is encoded in the genome of human.
Short Label hARHGAP23
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P227 (ARHGAP23) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y90 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
R180 Methylation PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
T212 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
T266 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
S361 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S372 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
S423 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S437 Phosphorylation PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S572 Phosphorylation phospho.ELM 18669648
S576 Phosphorylation phospho.ELM 18669648
T582 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S583 Phosphorylation phospho.ELM 18669648
S598 Phosphorylation PhosphoSitePlus
S602 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
Y612 Phosphorylation PhosphoSitePlus
T617 Phosphorylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus
T656 Phosphorylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus
K674 Ubiquitination PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus   UniProt 23186163
S682 Phosphorylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus
K703 Acetylation PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus
K824 Ubiquitination PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus
K854 Sumoylation PhosphoSitePlus
K854 Ubiquitination PhosphoSitePlus
K859 Methylation PhosphoSitePlus
K859 Ubiquitination PhosphoSitePlus
K876 Ubiquitination PhosphoSitePlus
K884 Ubiquitination PhosphoSitePlus
K987 Ubiquitination PhosphoSitePlus
K997 Ubiquitination PhosphoSitePlus
T1107 Phosphorylation PhosphoSitePlus
K1112 Ubiquitination PhosphoSitePlus
Y1122 Phosphorylation PhosphoSitePlus
T1130 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
T1141 Phosphorylation PhosphoSitePlus
T1142 Phosphorylation PhosphoSitePlus
S1144 Phosphorylation PhosphoSitePlus
S1145 Phosphorylation PhosphoSitePlus
T1189 Phosphorylation PhosphoSitePlus
S1230 Phosphorylation PhosphoSitePlus
T1243 Phosphorylation PhosphoSitePlus
S1306 Phosphorylation PhosphoSitePlus
S1308 Phosphorylation PhosphoSitePlus
S1309 Phosphorylation PhosphoSitePlus
T1317 Phosphorylation PhosphoSitePlus
R1335 Methylation PhosphoSitePlus
S1393 Phosphorylation PhosphoSitePlus
T1396 Phosphorylation PhosphoSitePlus
S1412 Phosphorylation PhosphoSitePlus
S1448 Phosphorylation PhosphoSitePlus
S1449 Phosphorylation PhosphoSitePlus
S1452 Phosphorylation PhosphoSitePlus
T1453 Phosphorylation PhosphoSitePlus
K1454 Ubiquitination PhosphoSitePlus
S1459 Phosphorylation PhosphoSitePlus
S1460 Phosphorylation PhosphoSitePlus
S1482 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K122 R122 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y163 N163 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S164 F164 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
R180 C180 Biomuta DOID:363 / uterine cancer [ tcga ]
T212 I212 Biomuta DOID:363 / uterine cancer [ tcga ]
S262 L262 Biomuta DOID:1909 / melanoma [ cosmic ]
T266 M266 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K703 * Biomuta DOID:363 / uterine cancer [ tcga ]
K703 N703 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y1122 H1122 Biomuta DOID:363 / uterine cancer [ tcga ]
S1309 * Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]