iPTMnet Report for Q9P219 (CCDC88C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P219 / DAPLE_HUMAN
Protein Name Protein Daple
Gene Name Name: CCDC88C
Synonyms:DAPLE,KIAA1509;
Organism Homo sapiens (Human)

PRO ID PR:Q9P219
DAG View
PRO Name protein Daple (human)
Definition A protein Daple that is encoded in the genome of human.
Short Label hCCDC88C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P219 (CCDC88C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K65 Ubiquitination PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
Y219 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus   UniProt 23186163
S239 Phosphorylation PhosphoSitePlus   UniProt 23186163
S446 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
K470 Ubiquitination PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus   UniProt 23186163
K495 Ubiquitination PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
S581 Phosphorylation PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
K700 Ubiquitination PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
K891 Acetylation PhosphoSitePlus
K898 Acetylation PhosphoSitePlus
S1023 Phosphorylation PhosphoSitePlus
K1073 Ubiquitination PhosphoSitePlus
S1193 Phosphorylation PhosphoSitePlus
K1196 Ubiquitination PhosphoSitePlus
T1231 Phosphorylation PhosphoSitePlus
Y1272 Phosphorylation PhosphoSitePlus
C1321 Methylation IEDB 31844290
K1387 Ubiquitination PhosphoSitePlus
Y1395 Phosphorylation IEDB   PhosphoSitePlus 32387766
K1409 Ubiquitination PhosphoSitePlus
S1428 Phosphorylation PhosphoSitePlus   RLIMS-P 29021338
T1429 Phosphorylation PhosphoSitePlus
S1432 Phosphorylation PhosphoSitePlus
S1440 Phosphorylation PhosphoSitePlus
S1444 Phosphorylation PhosphoSitePlus   UniProt 19690332
T1460 Phosphorylation PhosphoSitePlus
S1477 Phosphorylation PhosphoSitePlus
S1491 Phosphorylation PhosphoSitePlus
S1496 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 29237092
S1496 Phosphorylation PhosphoSitePlus
S1510 Phosphorylation PhosphoSitePlus
S1513 Phosphorylation PhosphoSitePlus
T1519 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 29237092
S1521 Phosphorylation PhosphoSitePlus
S1523 O-Glycosylation GlyGen 30379171, 32938750, 30059200, ...35254053, 34019948, 31492838, 29237092
S1530 Phosphorylation PhosphoSitePlus
T1533 Phosphorylation PhosphoSitePlus
T1542 Phosphorylation PhosphoSitePlus
S1547 Phosphorylation PhosphoSitePlus
S1555 Phosphorylation PhosphoSitePlus
S1571 Phosphorylation PhosphoSitePlus
S1572 Phosphorylation PhosphoSitePlus
S1580 Phosphorylation PhosphoSitePlus
S1584 Phosphorylation PhosphoSitePlus
S1591 Phosphorylation PhosphoSitePlus
S1601 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1603 Phosphorylation PhosphoSitePlus
S1604 Phosphorylation PhosphoSitePlus
S1610 Phosphorylation PhosphoSitePlus
T1615 Phosphorylation PhosphoSitePlus
T1622 Phosphorylation PhosphoSitePlus
T1671 Phosphorylation PhosphoSitePlus
S1683 Phosphorylation PhosphoSitePlus
Y1699 Phosphorylation PhosphoSitePlus
S1704 Phosphorylation PhosphoSitePlus
S1740 Phosphorylation PhosphoSitePlus
S1778 Phosphorylation PhosphoSitePlus
S1791 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 29237092
S1806 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1825 Phosphorylation PhosphoSitePlus
S1847 Phosphorylation PhosphoSitePlus
T1861 Phosphorylation PhosphoSitePlus
R1877 Methylation PhosphoSitePlus
S1887 Phosphorylation PhosphoSitePlus
S1930 Phosphorylation PhosphoSitePlus
T1954 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1963 Phosphorylation PhosphoSitePlus
S1981 Phosphorylation PhosphoSitePlus
S1985 Phosphorylation PhosphoSitePlus
S2003 Phosphorylation PhosphoSitePlus
S2011 Phosphorylation PhosphoSitePlus
Y2023 Phosphorylation PhosphoSitePlus   RLIMS-P 32058970
Y2025 Phosphorylation PhosphoSitePlus   RLIMS-P 32058970
Site PTM Type PTM Enzyme Score Source PMID
S227 Phosphorylation HPRD 19651622
S233 Phosphorylation HPRD 18452278
S236 Phosphorylation HPRD 18452278
S243 Phosphorylation HPRD 18452278
S681 Phosphorylation HPRD 20068231
S1599 Phosphorylation HPRD 20068231
S1610 Phosphorylation HPRD 20068231
S1806 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S239 I239 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S243 I243 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S452 L452 Biomuta DOID:363 / uterine cancer [ cosmic ]
S681 Y681 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1023 Y1023 Biomuta DOID:363 / uterine cancer [ icgc ]
K1387 N1387 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y1395 C1395 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1428 F1428 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1477 Y1477 Biomuta DOID:363 / uterine cancer [ icgc ]
S1477 F1477 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1491 F1491 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1496 I1496 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S1521 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1584 L1584 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S1591 F1591 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1610 N1610 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1740 L1740 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S1791 F1791 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1877 C1877 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1963 L1963 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
Y2023 N2023 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]