iPTMnet Report for Q9P1W8 (SIRPG)
Protein Information
| UniProt AC / UniProt ID | Q9P1W8 / SIRPG_HUMAN |
| Protein Name | Signal-regulatory protein gamma precursor |
| Gene Name | Name: SIRPG Synonyms:SIRPB2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9P1W8 |
| PRO Name | signal-regulatory protein gamma (human) |
| Definition | A signal-regulatory protein gamma that is encoded in the genome of human. |
| Short Label | hSIRPG |
| Category | organism-gene |
Q9P1W8 (SIRPG) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S147 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T163 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N243 | N-Glycosylation | score2 | GlyGen UniProt | 19349973 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S222 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K81 | N81 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ] | |
| T138 | N138 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S147 | P147 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T163 | R163 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S206 | N206 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S222 | F222 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View