iPTMnet Report for Q9P1T7 (MDFIC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P1T7 / MDFIC_HUMAN
Protein Name MyoD family inhibitor domain-containing protein
Gene Name Name: MDFIC
Organism Homo sapiens (Human)

PRO ID PR:Q9P1T7
DAG View
PRO Name MyoD family inhibitor domain-containing protein (human)
Definition A MyoD family inhibitor domain-containing protein that is encoded in the genome of human.
Short Label hMDFIC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P1T7 (MDFIC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus   UniProt 23186163
K130 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S143 Phosphorylation PhosphoSitePlus   UniProt 23186163
S146 Phosphorylation PhosphoSitePlus
K147 Acetylation PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
S149 Phosphorylation IEDB   PhosphoSitePlus 31848261
K150 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T8 Phosphorylation PhosphoSitePlus
T15 Phosphorylation PhosphoSitePlus
S18 Phosphorylation HPRD 18767875
S249 Phosphorylation HPRD 19651622, 18669648
S252 Phosphorylation HPRD 19651622, 18578522, 18669648
S255 Phosphorylation HPRD 18578522


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K122 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S124 L124 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S128 P128 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S128 F128 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K130 N130 Biomuta DOID:263 / kidney cancer [ cosmic ]
K147 R147 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K147 T147 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K150 E150 Biomuta DOID:1324 / lung cancer [ cosmic ]