iPTMnet Report for Q9P0P0 (RNF181)
Protein Information
| UniProt AC / UniProt ID | Q9P0P0 / RN181_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase RNF181 |
| Gene Name | Name: RNF181 ORFNames:HSPC238; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9P0P0 |
| PRO Name | E3 ubiquitin-protein ligase RNF181 (human) |
| Definition | An E3 ubiquitin-protein ligase RNF181 that is encoded in the genome of human. |
| Short Label | hRNF181 |
| Category | organism-gene |
DAG ViewQ9P0P0 (RNF181) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y4 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S70 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17525332 | ||
| C94 | Methylation | score1 | IEDB | 31844290 | ||
| Y127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T153 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S13 | P13 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S70 | A70 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| Y127 | D127 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T153 | M153 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ] |
