iPTMnet Report for Q9P0K1 (ADAM22)
Protein Information
| UniProt AC / UniProt ID | Q9P0K1 / ADA22_HUMAN |
| Protein Name | Disintegrin and metalloproteinase domain-containing protein 22 precursor |
| Gene Name | Name: ADAM22 Synonyms:MDC2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9P0K1 |
| PRO Name | disintegrin and metalloproteinase domain-containing protein 22 (human) |
| Definition | A disintegrin and metalloproteinase domain-containing protein 22 that is encoded in the genome of human. |
| Short Label | hADAM22 |
| Category | organism-gene |
DAG ViewQ9P0K1 (ADAM22) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T262 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T264 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S302 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T308 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C349 | Methylation | score1 | IEDB | 31844290 | ||
| N519 | N-Glycosylation | score4 | GlyGen UniProt | 19692335, 24190977 | ||
| Y556 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S565 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N634 | N-Glycosylation | score3 | GlyGen UniProt | 19692335 | ||
| N675 | N-Glycosylation | score3 | GlyGen UniProt | 19692335 | ||
| S812 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S822 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S832 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S834 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
| S855 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S857 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T858 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T860 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S869 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S870 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T871 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S873 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y880 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y882 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S834 | Phosphorylation | score0 | HPRD | 19664994 | ||
| S869 | Phosphorylation | score0 | HPRD | 19413330 | ||
| S870 | Phosphorylation | score0 | HPRD | 19413330 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S798 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19664994 | ||
| S819 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S821 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y824 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y833 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y850 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S862 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330 | ||
| S863 | Phosphorylation | score0 | HPRD | 19413330 | ||
| S866 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S32 | L32 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T264 | N264 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S302 | Y302 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T308 | A308 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S798 | P798 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S819 | F819 | Biomuta | DOID:184 / bone cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] | |
| S822 | L822 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S834 | P834 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S855 | F855 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| T860 | A860 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] |
