iPTMnet Report for Q9P0I2 (EMC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P0I2 / EMC3_HUMAN
Protein Name ER membrane protein complex subunit 3
Gene Name Name: EMC3
Synonyms:TMEM111;
Organism Homo sapiens (Human)

PRO ID PR:Q9P0I2
DAG View
PRO Name ER membrane protein complex subunit 3 (human)
Definition An ER membrane protein complex subunit 3 that is encoded in the genome of human.
Short Label hEMC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9P0I2 (EMC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K43 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
K216 Methylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T145 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K66 I66 Biomuta DOID:263 / kidney cancer [ cosmic ]
S99 Y99 Biomuta DOID:363 / uterine cancer [ icgc ]
T108 A108 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
T108 I108 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T145 I145 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K216 N216 Biomuta DOID:9256 / colorectal cancer [ cosmic ]