iPTMnet Report for Q9NZZ3 (CHMP5)
Protein Information
| UniProt AC / UniProt ID | Q9NZZ3 / CHMP5_HUMAN |
| Protein Name | Charged multivesicular body protein 5 |
| Gene Name | Name: CHMP5 Synonyms:C9orf83,SNF7DC2;ORFNames:CGI-34,HSPC177,PNAS-114,PNAS-2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NZZ3 |
| PRO Name | charged multivesicular body protein 5 (human) |
| Definition | A charged multivesicular body protein 5 that is encoded in the genome of human. |
| Short Label | hCHMP5 |
| Category | organism-gene |
Q9NZZ3 (CHMP5) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| R3 | Methylation | score1 | PhosphoSitePlus | |||
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T18 | O-Glycosylation | score1 | GlyGen | 23301498, 34019948, 35132862 | ||
| T18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C20 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| T23 | O-Glycosylation | score1 | GlyGen | 23301498, 34019948, 35132862 | ||
| S30 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S86 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| Y94 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T95 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K110 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S219 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S16 | I16 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| C20 | Y20 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| Y94 | F94 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S98 | C98 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View