iPTMnet Report for Q9NZW5 (PALS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZW5 / PALS2_HUMAN
Protein Name Protein PALS2
Gene Name Name: PALS2
Synonyms:MPP6,VAM1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZW5
DAG View
PRO Name protein PALS2 (human)
Definition A protein PALS2 that is encoded in the genome of human.
Short Label hPALS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZW5 (PALS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y104 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
R136 Methylation PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
T202 Phosphorylation PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
Y311 Phosphorylation PhosphoSitePlus
R321 Methylation PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
Y410 Phosphorylation PhosphoSitePlus
Y415 Phosphorylation PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
T446 Phosphorylation PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
Y500 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 15592455
K515 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S110 G110 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R136 K136 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K242 R242 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y311 H311 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y311 S311 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R321 S321 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R321 C321 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R321 H321 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S493 N493 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y500 C500 Biomuta DOID:363 / uterine cancer [ icgc ]
K515 R515 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K515 N515 Biomuta DOID:9256 / colorectal cancer [ cosmic ]