iPTMnet Report for Q9NZV8 (KCND2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZV8 / KCND2_HUMAN
Protein Name Potassium voltage-gated channel subfamily D member 2
Gene Name Name: KCND2
Synonyms:KIAA1044;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZV8
DAG View
PRO Name potassium voltage-gated channel subfamily D member 2 (human)
Definition A voltage-gated potassium channel KCND2 that is encoded in the genome of human.
Short Label hKCND2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZV8 (KCND2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T38 Phosphorylation neXtProt 1519755
Y134 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S438 Phosphorylation phospho.ELM   PhosphoSitePlus 15071113
S440 Phosphorylation PhosphoSitePlus
Y444 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
S459 Phosphorylation phospho.ELM 15071113
T537 Phosphorylation PhosphoSitePlus
S552 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   RLIMS-P 20045463, 1519755
K579 Sumoylation PhosphoSitePlus
T602 Phosphorylation P28482 (MAPK1) neXtProt   RLIMS-P 16251476, 11080179
T607 Phosphorylation P28482 (MAPK1) neXtProt   RLIMS-P 16251476, 11080179
S616 Phosphorylation P28482 (MAPK1) neXtProt   RLIMS-P 16251476, 11080179


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S260 R260 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S438 R438 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S438 N438 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y444 C444 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S447 I447 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T537 A537 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S552 N552 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K579 E579 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]