iPTMnet Report for Q9NZV1 (CRIM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZV1 / CRIM1_HUMAN
Protein Name Cysteine-rich motor neuron 1 protein precursor
Gene Name Name: CRIM1
Synonyms:S52;ORFNames:UNQ1886/PRO4330;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZV1
DAG View
PRO Name cysteine-rich motor neuron 1 protein (human)
Definition A cysteine-rich motor neuron 1 protein that is encoded in the genome of human.
Short Label hCRIM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZV1 (CRIM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation IEDB 32387766
K44 Ubiquitination PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
S73 O-Glycosylation GlyGen 35289036
T77 O-Glycosylation GlyGen 35289036
K176 Ubiquitination PhosphoSitePlus
S596 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S596 Phosphorylation PhosphoSitePlus
S598 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
S598 Phosphorylation PhosphoSitePlus
Y630 Phosphorylation PhosphoSitePlus
N746 N-Glycosylation GlyGen 23090970, 24190977
S748 O-Glycosylation GlyGen 35289036
Y807 Phosphorylation PhosphoSitePlus
K816 Ubiquitination PhosphoSitePlus
Y826 Phosphorylation PhosphoSitePlus
T882 O-Glycosylation GlyGen 25813380
T889 O-Glycosylation GlyGen 25813380
T904 O-Glycosylation GlyGen 30459171
K978 Ubiquitination PhosphoSitePlus
S988 Phosphorylation PhosphoSitePlus
T995 Phosphorylation PhosphoSitePlus
Y1019 Phosphorylation PhosphoSitePlus
S1020 Phosphorylation PhosphoSitePlus
K1023 Ubiquitination PhosphoSitePlus
Y1033 Phosphorylation PhosphoSitePlus
T1035 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K44 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
K44 N44 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T77 I77 Biomuta [ cosmic ]
Y630 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
N746 S746 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y826 S826 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S988 T988 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]