iPTMnet Report Q9NZT2 OGFR

Protein Information

UniProt AC / UniProt ID	Q9NZT2 / OGFR_HUMAN
Protein Name	Opioid growth factor receptor
Gene Name	Name: OGFR
Organism	Homo sapiens (Human)

PRO ID	PR:Q9NZT2 DAG View
PRO Name	opioid growth factor receptor (human)
Definition	An opioid growth factor receptor that is encoded in the genome of human.
Short Label	hOGFR
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9NZT2 (OGFR) as Substrate

Expanded View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position M1 S45 S55 K158 Y171 Y178 T187 T189 Y196 K198 K218 K283 K291 K296 S299 K309 S315 S324 T325 T329 S349 S361 S378 S382 S390 S403 S420 S423 T426 T428 K454 T478 S484 S488 S496 S517 S525 S537 S557 S577 T581 S585 S597 S617 S637 T641 S645 T650	PTM Type Select all Acetylation Phosphorylation Sumoylation Ubiquitination	PTM Enzyme	Score Select all 1 2	Source Select all PhosphoSitePlus UniProt phospho.ELM	PMID
M1	Acetylation		score1	UniProt	19413330
S45	Phosphorylation		score1	PhosphoSitePlus
S55	Phosphorylation		score1	PhosphoSitePlus
K158	Ubiquitination		score1	PhosphoSitePlus
Y171	Phosphorylation		score1	PhosphoSitePlus
Y178	Phosphorylation		score1	PhosphoSitePlus
T187	Phosphorylation		score1	PhosphoSitePlus
T189	Phosphorylation		score1	PhosphoSitePlus
Y196	Phosphorylation		score1	PhosphoSitePlus
K198	Ubiquitination		score1	PhosphoSitePlus
K218	Ubiquitination		score1	PhosphoSitePlus
K283	Ubiquitination		score1	PhosphoSitePlus
K291	Ubiquitination		score1	PhosphoSitePlus
K296	Ubiquitination		score1	PhosphoSitePlus
S299	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
K309	Sumoylation		score1	PhosphoSitePlus
S315	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	21406692, 23186163, 17081983, ...24275569, 17287340, 20068231
S324	Phosphorylation		score1	PhosphoSitePlus
T325	Phosphorylation		score1	PhosphoSitePlus
T329	Phosphorylation		score1	PhosphoSitePlus
S349	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 23186163
S361	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 23186163, 20068231
S378	Phosphorylation	P06493 (CDK1)	score2	phospho.ELM PhosphoSitePlus UniProt	19369195, 21406692, 23186163, ...18234856, 18318008, 18669648, 24275569, 19690332, 20068231
S382	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
S390	Phosphorylation		score1	PhosphoSitePlus
S403	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
S420	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	17525332
S423	Phosphorylation		score1	PhosphoSitePlus
T426	Phosphorylation		score1	PhosphoSitePlus
T428	Phosphorylation		score1	PhosphoSitePlus
K454	Acetylation		score1	PhosphoSitePlus
T478	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18669648
S484	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 23186163, 20068231
S488	Phosphorylation		score1	PhosphoSitePlus
S496	Phosphorylation		score1	PhosphoSitePlus
S517	Phosphorylation		score1	PhosphoSitePlus
S525	Phosphorylation		score1	PhosphoSitePlus
S537	Phosphorylation		score2	PhosphoSitePlus UniProt	20068231
S557	Phosphorylation		score2	PhosphoSitePlus UniProt	20068231
S577	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18220336
T581	Phosphorylation		score1	PhosphoSitePlus
S585	Phosphorylation		score1	PhosphoSitePlus
S597	Phosphorylation		score1	PhosphoSitePlus
S617	Phosphorylation		score2	PhosphoSitePlus UniProt	20068231
S637	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18220336
T641	Phosphorylation		score1	PhosphoSitePlus
S645	Phosphorylation		score1	PhosphoSitePlus
T650	Phosphorylation		score1	PhosphoSitePlus

Search:

Site Select all By amino acid All Serine All Threonine By position S315 S349 S361 S378 S420 T428 T478 S484 S517	PTM Type Select all Phosphorylation	Score Select all 0	Source Select all HPRD	PMID
S315	Phosphorylation	score0	HPRD	19413330, 18491316, 17287340, ...17081983, 19651622, 18510355, 18707149, 20166139, 19415658, 20068231, 18212344
S349	Phosphorylation	score0	HPRD	18669648, 20058876, 18212344, ...20068231
S361	Phosphorylation	score0	HPRD	18669648, 20068231
S378	Phosphorylation	score0	HPRD	18491316, 17081983, 18767875, ...19651622, 18510355, 18669648, 18707149, 20166139, 20068231
S420	Phosphorylation	score0	HPRD	17525332, 18077418, 20068231
T428	Phosphorylation	score0	HPRD	18077418
T478	Phosphorylation	score0	HPRD	18669648, 20068231
S484	Phosphorylation	score0	HPRD	18669648, 20068231
S517	Phosphorylation	score0	HPRD	19664994, 20068231

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine By position S45 K158 S378 S403 T426 S496 S525 S537 S557 S577 T581 S585 S637 T641 S645 T650	Variant Select all A641 A650 C403 I378 M426 N496 P581 R158 R525 R585 R645 T537 T557 T577 T637 W45	Source Select all Biomuta	Disease [Sample source] Select all DOID:10283 / prostate cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
S45	W45	Biomuta	DOID:1793 / pancreatic cancer [ cosmic ]
K158	R158	Biomuta	DOID:10283 / prostate cancer [ cosmic ]
S378	I378	Biomuta	DOID:263 / kidney cancer [ cosmic, icgc ]
S403	C403	Biomuta	DOID:1324 / lung cancer [ cosmic ]
T426	M426	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
S496	N496	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S525	R525	Biomuta	DOID:3571 / liver cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S537	T537	Biomuta	DOID:3571 / liver cancer [ cosmic ]
S557	T557	Biomuta	DOID:10283 / prostate cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
S577	T577	Biomuta	DOID:1781 / thyroid cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
T581	P581	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
S585	R585	Biomuta	DOID:263 / kidney cancer [ cosmic ]
S637	T637	Biomuta	[ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
T641	A641	Biomuta	DOID:363 / uterine cancer [ icgc ]
S645	R645	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
T650	A650	Biomuta	DOID:1319 / brain cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q9NZT2 (OGFR)

Protein Information

Interactive Sequence View

Q9NZT2 (OGFR) as Substrate

PTM sites affected in variants