Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZR2 / LRP1B_HUMAN
Protein Name Low-density lipoprotein receptor-related protein 1B precursor
Gene Name Name: LRP1B
Synonyms:LRPDIT;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZR2
DAG View
PRO Name low-density lipoprotein receptor-related protein 1B (human)
Definition A low-density lipoprotein receptor-related protein 1B that is encoded in the genome of human.
Short Label hLRP1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZR2 (LRP1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y390 Phosphorylation PhosphoSitePlus
Y1621 Phosphorylation PhosphoSitePlus
T1627 Phosphorylation PhosphoSitePlus
T1629 Phosphorylation PhosphoSitePlus
Y1708 Phosphorylation PhosphoSitePlus
T1710 Phosphorylation PhosphoSitePlus
T1784 Phosphorylation PhosphoSitePlus
N1983 N-Glycosylation GlyGen 29741879
R1999 Methylation PhosphoSitePlus
R2109 Methylation PhosphoSitePlus
S2581 Phosphorylation PhosphoSitePlus
T3593 Phosphorylation PhosphoSitePlus
Y3617 Phosphorylation PhosphoSitePlus
S3623 Phosphorylation PhosphoSitePlus
R3727 Methylation PhosphoSitePlus
Y4006 Phosphorylation PhosphoSitePlus
S4007 Phosphorylation PhosphoSitePlus
T4023 Phosphorylation PhosphoSitePlus
K4068 Acetylation PhosphoSitePlus
Y4150 Phosphorylation HPRD   PhosphoSitePlus 19664994, 18452278
Y4562 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y1621 * Biomuta DOID:3571 / liver cancer [ icgc ]
T1627 A1627 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic ]
Y1708 N1708 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
T1784 A1784 Biomuta DOID:363 / uterine cancer [ tcga ]
R1999 K1999 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S4007 Y4007 Biomuta DOID:1324 / lung cancer [ tcga ]
K4068 N4068 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K4068 R4068 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y4150 * Biomuta DOID:5041 / esophageal cancer [ icgc ]
Y4562 F4562 Biomuta DOID:263 / kidney cancer [ cosmic ]