iPTMnet Report for Q9NZQ3 (NCKIPSD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZQ3 / SPN90_HUMAN
Protein Name NCK-interacting protein with SH3 domain
Gene Name Name: NCKIPSD
Synonyms:AF3P21,SPIN90;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZQ3
DAG View
PRO Name NCK-interacting protein with SH3 domain (human)
Definition A NCK-interacting protein with SH3 domain that is encoded in the genome of human.
Short Label hNCKIPSD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZQ3 (NCKIPSD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K84 Ubiquitination PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus   RLIMS-P 23765104, 23342115
K95 Ubiquitination PhosphoSitePlus
R107 Methylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
Y161 Phosphorylation P12931 (SRC) PhosphoSitePlus   RLIMS-P 23765104, 23342115
T180 Phosphorylation PhosphoSitePlus
T181 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18088087
Y227 Phosphorylation P12931 (SRC) PhosphoSitePlus   RLIMS-P 23765104, 23342115
T242 Phosphorylation PhosphoSitePlus
R249 Methylation PhosphoSitePlus
T251 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
T311 O-Glycosylation GlyGen 34019948, 28657654
T311 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
K584 Ubiquitination PhosphoSitePlus
Y673 Phosphorylation PhosphoSitePlus
K712 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T181 Phosphorylation HPRD 18088087
Site PTM Type PTM Enzyme Score Source PMID
S147 Phosphorylation PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
T174 Phosphorylation HPRD   PhosphoSitePlus 18088087


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R249 Q249 Biomuta DOID:4159 / skin cancer [ cosmic ]
T253 I253 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S256 F256 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S263 P263 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S263 F263 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y404 H404 Biomuta DOID:9256 / colorectal cancer [ cosmic ]