iPTMnet Report for Q9NZN4 (EHD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZN4 / EHD2_HUMAN
Protein Name EH domain-containing protein 2
Gene Name Name: EHD2
Synonyms:PAST2;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZN4
DAG View
PRO Name EH domain-containing protein 2 (human)
Definition An EH domain-containing protein 2 that is encoded in the genome of human.
Short Label hEHD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZN4 (EHD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Methylation PhosphoSitePlus
T20 Phosphorylation PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
K316 Methylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
K324 Methylation PhosphoSitePlus
K327 Methylation PhosphoSitePlus
K328 Acetylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
S438 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 15302935, ...18318008, 18669648, 24275569
S451 Phosphorylation PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
Y458 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S468 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S470 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K473 Ubiquitination PhosphoSitePlus
T474 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus   UniProt 23186163
K516 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S438 Phosphorylation HPRD 15302935, 18452278, 19651622, ...18669648, 20166139, 15345747, 19415658
S468 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
S470 Phosphorylation HPRD 18669648, 17081983, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T22 A22 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S23 L23 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y313 N313 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S438 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S470 F470 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]