iPTMnet Report for Q9NZM5 (NOP53)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZM5 / NOP53_HUMAN
Protein Name Ribosome biogenesis protein NOP53
Gene Name Name: NOP53
Synonyms:GLT;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZM5
DAG View
PRO Name ribosome biogenesis protein NOP53 (human)
Definition A ribosome biogenesis protein NOP53 that is encoded in the genome of human.
Short Label hNOP53
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZM5 (NOP53) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S6 Phosphorylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
T28 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S29 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
R35 Methylation PhosphoSitePlus
T73 Phosphorylation HPRD   phospho.ELM 18669648
K85 Ubiquitination PhosphoSitePlus
T91 Phosphorylation HPRD   PhosphoSitePlus 20068231
S93 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T103 Phosphorylation PhosphoSitePlus
K104 Acetylation PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
T178 Phosphorylation PhosphoSitePlus
R204 Methylation PhosphoSitePlus
S233 Phosphorylation Q13315 (ATM) PhosphoSitePlus   RLIMS-P   Signor 27829214
T256 Phosphorylation PhosphoSitePlus
T289 Phosphorylation Q13315 (ATM) PhosphoSitePlus   RLIMS-P   Signor 27829214
C325 Methylation IEDB 31844290
K375 Ubiquitination PhosphoSitePlus
R381 Methylation PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 N13 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S14 L14 Biomuta DOID:1324 / lung cancer [ cosmic ]
T28 A28 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K107 N107 Biomuta DOID:3571 / liver cancer [ cosmic ]