iPTMnet Report for Q9NZL9 (MAT2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZL9 / MAT2B_HUMAN
Protein Name Methionine adenosyltransferase 2 subunit beta
Gene Name Name: MAT2B
Synonyms:TGR;ORFNames:MSTP045,Nbla02999,UNQ2435/PRO4995;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZL9
DAG View
PRO Name methionine adenosyltransferase 2 subunit beta (human)
Definition A methionine adenosyltransferase 2 subunit beta that is encoded in the genome of human.
Short Label hMAT2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZL9 (MAT2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
S9 Phosphorylation PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
K46 Acetylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
Y186 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
C231 Methylation IEDB 31844290
S243 O-Glycosylation GlyGen 33214551, 30379171, 34725712, ...34019948, 28510447, 34229054
K245 Ubiquitination PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
S282 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
C297 Methylation IEDB 31844290
K299 Acetylation PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
T309 Phosphorylation PhosphoSitePlus   UniProt 23186163
K316 Ubiquitination PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S282 Phosphorylation HPRD 18669648, 19664994
Site PTM Type PTM Enzyme Score Source PMID
S271 Phosphorylation HPRD 18669648, 19664994


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048342 (hMAT2B/InitMet-/UbiqLys+) ub PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 C9 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K209 E209 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
C231 R231 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T309 A309 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]