iPTMnet Report for Q9NZL3 (ZNF224)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZL3 / ZN224_HUMAN
Protein Name Zinc finger protein 224
Gene Name Name: ZNF224
Synonyms:BMZF2,KOX22,ZNF233,ZNF255,ZNF27;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZL3
DAG View
PRO Name zinc finger protein 224 (human)
Definition A zinc finger protein 224 that is encoded in the genome of human.
Short Label hZNF224
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZL3 (ZNF224) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Sumoylation PhosphoSitePlus
K31 Sumoylation PhosphoSitePlus
T227 Phosphorylation PhosphoSitePlus
K233 Sumoylation PhosphoSitePlus
S245 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
T255 Phosphorylation PhosphoSitePlus
K258 Sumoylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
T339 Phosphorylation PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
K345 Sumoylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
T367 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
K401 Sumoylation PhosphoSitePlus
K454 Sumoylation PhosphoSitePlus
K459 Sumoylation PhosphoSitePlus
K473 Sumoylation PhosphoSitePlus
T507 Phosphorylation PhosphoSitePlus
K510 Sumoylation PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
Y521 Phosphorylation PhosphoSitePlus
K524 Sumoylation PhosphoSitePlus
T535 Phosphorylation PhosphoSitePlus
K557 Sumoylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
K566 Acetylation PhosphoSitePlus
K566 Sumoylation PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K569 Sumoylation PhosphoSitePlus
T591 Phosphorylation PhosphoSitePlus
K594 Sumoylation PhosphoSitePlus
K594 Ubiquitination PhosphoSitePlus
K625 Sumoylation PhosphoSitePlus
K640 Acetylation PhosphoSitePlus
K640 Sumoylation PhosphoSitePlus
K650 Acetylation PhosphoSitePlus
K653 Sumoylation PhosphoSitePlus
K678 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 E5 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K233 I233 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T255 I255 Biomuta DOID:363 / uterine cancer [ icgc ]
T283 M283 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ]
K342 N342 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K459 N459 Biomuta DOID:4159 / skin cancer [ cosmic ]
K569 * Biomuta [ cosmic ]
K650 N650 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]