iPTMnet Report for Q9NZI5 (GRHL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZI5 / GRHL1_HUMAN
Protein Name Grainyhead-like protein 1 homolog
Gene Name Name: GRHL1
Synonyms:LBP32,MGR,TFCP2L2;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZI5
DAG View
PRO Name grainyhead-like protein 1 homolog (human)
Definition A grainyhead-like protein 1 that is encoded in the genome of human.
Short Label hGRHL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZI5 (GRHL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
Y65 Phosphorylation PhosphoSitePlus
Y67 Phosphorylation PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus   RLIMS-P 33931584
S77 Phosphorylation PhosphoSitePlus   RLIMS-P 33931584
S95 Phosphorylation PhosphoSitePlus
T146 O-Glycosylation GlyGen 35254053
T208 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 33931584, 23186163
Y414 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus
K573 Acetylation PhosphoSitePlus
K576 Acetylation PhosphoSitePlus
Y594 Phosphorylation PhosphoSitePlus
Y611 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y65 C65 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S76 P76 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S76 L76 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
Y594 C594 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]