iPTMnet Report Q9NZD8 SPG21

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9NZD8 / SPG21_HUMAN
Protein Name	Maspardin
Gene Name	Name: SPG21 Synonyms:ACP33;ORFNames:BM-019,GL010;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9NZD8 DAG View
PRO Name	maspardin (human)
Definition	A maspardin that is encoded in the genome of human.
Short Label	hSPG21
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9NZD8 (SPG21) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K5	Ubiquitination		score1	PhosphoSitePlus
	K21	Ubiquitination		score1	PhosphoSitePlus
	K30	Ubiquitination		score1	PhosphoSitePlus
	K124	Ubiquitination		score1	PhosphoSitePlus
	K213	Ubiquitination		score1	PhosphoSitePlus
	K235	Ubiquitination		score1	PhosphoSitePlus
	K240	Ubiquitination		score1	PhosphoSitePlus
	K251	Ubiquitination		score1	PhosphoSitePlus
	S290	Phosphorylation		score1	PhosphoSitePlus
	K298	Ubiquitination		score1	PhosphoSitePlus
	S300	Phosphorylation		score1	PhosphoSitePlus
	S304	Phosphorylation		score2	PhosphoSitePlus UniProt	20068231

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S304	Phosphorylation		score0	HPRD	19413330, 18077418, 20068231

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K213	R213	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
S300	I300	Biomuta		DOID:263 / kidney cancer [ cosmic, icgc ]
S304	N304	Biomuta		DOID:4159 / skin cancer [ cosmic ]