iPTMnet Report for Q9NZC9 (SMARCAL1)
Protein Information
| UniProt AC / UniProt ID | Q9NZC9 / SMAL1_HUMAN |
| Protein Name | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 |
| Gene Name | Name: SMARCAL1 Synonyms:HARP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NZC9 |
| PRO Name | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (human) |
| Definition | A SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 that is encoded in the genome of human. |
| Short Label | hSMARCAL1 |
| Category | organism-gene |
Q9NZC9 (SMARCAL1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 22814378 | ||
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K72 | Methylation | score1 | PhosphoSitePlus | |||
| S112 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| T120 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S123 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S129 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S151 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20068231 | ||
| K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S172 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 24150942 | ||
| S173 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 24150942 | ||
| S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S198 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N203 | N-Glycosylation | score1 | GlyGen | 29992770 | ||
| S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K225 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K232 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K275 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y306 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C388 | Methylation | score1 | IEDB | 31844290 | ||
| K411 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K431 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S528 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S533 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K555 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K570 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S627 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K647 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S652 | Phosphorylation | Q13535 (ATR) | score3 | neXtProt PhosphoSitePlus RLIMS-P Signor | 23873943 | |
| K657 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K660 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K682 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K849 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T867 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y872 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y874 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K881 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K888 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S889 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 24150942 | ||
| S934 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S952 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S112 | N112 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S173 | Y173 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S181 | C181 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S200 | L200 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| N203 | K203 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| K411 | N411 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S533 | R533 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| K555 | R555 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K570 | N570 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S652 | F652 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y874 | S874 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |
DAG View