iPTMnet Report for Q9NZB2 (FAM120A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZB2 / F120A_HUMAN
Protein Name Constitutive coactivator of PPAR-gamma-like protein 1
Gene Name Name: FAM120A
Synonyms:C9orf10,KIAA0183,OSSA;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZB2
DAG View
PRO Name constitutive coactivator of PPAR-gamma-like protein 1 (human)
Definition A constitutive coactivator of PPAR-gamma-like protein 1 that is encoded in the genome of human.
Short Label hFAM120A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZB2 (FAM120A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y9 Phosphorylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
C14 S-Nitrosylation dbSNO 2212679, 22126794
K25 Ubiquitination PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
T42 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
Y328 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
Y342 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
Y393 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
Y395 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
S417 Phosphorylation PhosphoSitePlus
Y418 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
T428 Phosphorylation PhosphoSitePlus
Y431 Phosphorylation PhosphoSitePlus
S434 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S435 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S442 Phosphorylation PhosphoSitePlus
S444 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K484 Ubiquitination PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
T508 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus
S638 Phosphorylation PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
T655 Phosphorylation PhosphoSitePlus   UniProt 23186163
K673 Ubiquitination PhosphoSitePlus
K679 Ubiquitination PhosphoSitePlus
Y721 Phosphorylation PhosphoSitePlus
S745 Phosphorylation PhosphoSitePlus
K758 Ubiquitination PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
K818 Ubiquitination PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
S841 Phosphorylation PhosphoSitePlus
S847 Phosphorylation PhosphoSitePlus
S852 Phosphorylation PhosphoSitePlus
T854 Phosphorylation PhosphoSitePlus
R873 Methylation PhosphoSitePlus   UniProt 24129315
R884 Methylation PhosphoSitePlus   UniProt 24129315
R886 Methylation PhosphoSitePlus   UniProt 24129315
R908 Methylation PhosphoSitePlus
R911 Methylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
C919 S-Nitrosylation dbSNO 26338901
S923 Phosphorylation PhosphoSitePlus
S925 Phosphorylation PhosphoSitePlus
S927 Phosphorylation PhosphoSitePlus
K932 Ubiquitination PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus
S942 Phosphorylation PhosphoSitePlus
T952 Phosphorylation PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus   UniProt 24275569
R964 Methylation PhosphoSitePlus
R967 Methylation PhosphoSitePlus
R982 Methylation PhosphoSitePlus   UniProt 24129315
R984 Methylation PhosphoSitePlus
R986 Methylation PhosphoSitePlus   UniProt 24129315
T991 Phosphorylation phospho.ELM   PhosphoSitePlus 16964243
R995 Methylation PhosphoSitePlus
T996 Phosphorylation PhosphoSitePlus
R999 Methylation PhosphoSitePlus
R1002 Methylation PhosphoSitePlus
Y1003 Phosphorylation PhosphoSitePlus
Y1004 Phosphorylation PhosphoSitePlus
R1006 Methylation PhosphoSitePlus
Y1020 Phosphorylation PhosphoSitePlus
S1023 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S1033 Phosphorylation PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
S1038 Phosphorylation PhosphoSitePlus
S1040 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1044 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S1045 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1048 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S1067 Phosphorylation PhosphoSitePlus
T1068 Phosphorylation PhosphoSitePlus
S1075 Phosphorylation PhosphoSitePlus
S1077 Phosphorylation PhosphoSitePlus
K1086 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation HPRD 17924679
S383 Phosphorylation HPRD 18691976, 17081983, 20068231
Y393 Phosphorylation HPRD 15592455
Y395 Phosphorylation HPRD 15592455
S434 Phosphorylation HPRD 18669648, 20058876
S435 Phosphorylation HPRD 18669648
S444 Phosphorylation HPRD 18669648
S841 Phosphorylation HPRD 20068231
S847 Phosphorylation HPRD 20068231
S849 Phosphorylation HPRD 20068231
T991 Phosphorylation HPRD 16964243
S1040 Phosphorylation HPRD 18669648
S1044 Phosphorylation HPRD 18669648
S1048 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
Y478 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S297 C297 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S336 P336 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y342 C342 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S434 F434 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S489 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S511 L511 Biomuta DOID:4159 / skin cancer [ cosmic ]
S534 L534 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S652 C652 Biomuta DOID:1324 / lung cancer [ cosmic ]
K834 E834 Biomuta DOID:263 / kidney cancer [ cosmic ]
S852 I852 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S852 N852 Biomuta DOID:363 / uterine cancer [ cosmic ]
R908 C908 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R911 C911 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S942 P942 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S960 R960 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R964 C964 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R967 Q967 Biomuta DOID:263 / kidney cancer [ cosmic ]
R984 C984 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R984 H984 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
R984 S984 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1023 L1023 Biomuta DOID:1612 / breast cancer [ icgc ]
S1033 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S1038 L1038 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]