Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZ71 / RTEL1_HUMAN
Protein Name Regulator of telomere elongation helicase 1
Gene Name Name: RTEL1
Synonyms:C20orf41,KIAA1088,NHL;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZ71
DAG View
PRO Name regulator of telomere elongation helicase 1 (human)
Definition A regulator of telomere elongation helicase 1 that is encoded in the genome of human.
Short Label hRTEL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZ71 (RTEL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K35 Ubiquitination PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
Y347 Phosphorylation PhosphoSitePlus
T361 Phosphorylation PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
K595 Ubiquitination PhosphoSitePlus
K626 Ubiquitination PhosphoSitePlus
K659 Ubiquitination PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
K778 Ubiquitination PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
T786 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
K800 Ubiquitination PhosphoSitePlus
S847 Phosphorylation PhosphoSitePlus
S882 Phosphorylation PhosphoSitePlus
T1103 Phosphorylation PhosphoSitePlus
T1104 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y175 Phosphorylation HPRD 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S405 F405 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S411 F411 Biomuta DOID:1909 / melanoma [ tcga ]
K626 N626 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
K659 N659 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S882 R882 Biomuta DOID:363 / uterine cancer [ tcga ]