iPTMnet Report for Q9NZ53 (PODXL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZ53 / PDXL2_HUMAN
Protein Name Podocalyxin-like protein 2 precursor
Gene Name Name: PODXL2
ORFNames:UNQ1861/PRO3742;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZ53
DAG View
PRO Name podocalyxin-like protein 2 (human)
Definition A podocalyxin-like protein 2 that is encoded in the genome of human.
Short Label hPODXL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZ53 (PODXL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S79 O-Glycosylation GlyGen   UniProt 12889478
S134 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S144 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 23234360
S144 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
T209 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T209 Phosphorylation PhosphoSitePlus
S210 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S210 Phosphorylation PhosphoSitePlus
S211 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S212 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S212 Phosphorylation PhosphoSitePlus
T214 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T214 Phosphorylation PhosphoSitePlus
T218 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S220 Phosphorylation PhosphoSitePlus
T290 O-Glycosylation GlyGen 30459171
T312 O-Glycosylation GlyGen 30459171
T349 O-Glycosylation GlyGen 30459171
N480 N-Glycosylation GlyGen 23090970, 24190977
S492 Phosphorylation PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
K567 Ubiquitination PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus   UniProt 20068231
S582 Phosphorylation PhosphoSitePlus
S596 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
T209 Phosphorylation HPRD 18077418
S210 Phosphorylation HPRD 18077418
S212 Phosphorylation HPRD 18077418
S220 Phosphorylation HPRD 18077418
S570 Phosphorylation HPRD 20068231
S596 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S210 R210 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S210 T210 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K567 T567 Biomuta DOID:1324 / lung cancer [ cosmic ]
S582 G582 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]