Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYZ4 / SIGL8_HUMAN
Protein Name Sialic acid-binding Ig-like lectin 8 precursor
Gene Name Name: SIGLEC8
Synonyms:SAF2;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYZ4
DAG View
PRO Name sialic acid-binding Ig-like lectin 8 (human)
Definition A sialic acid-binding Ig-like lectin 8 that is encoded in the genome of human.
Short Label hSIGLEC8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYZ4 (SIGLEC8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S134 Phosphorylation PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S134 N134 Biomuta DOID:11934 / head and neck cancer [ tcga ]
Y141 S141 Biomuta DOID:5041 / esophageal cancer [ icgc ]