iPTMnet Report for Q9NYZ4 (SIGLEC8)
Protein Information
UniProt AC / UniProt ID | Q9NYZ4 / SIGL8_HUMAN |
Protein Name | Sialic acid-binding Ig-like lectin 8 precursor |
Gene Name | Name: SIGLEC8 Synonyms:SAF2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NYZ4 |
PRO Name | sialic acid-binding Ig-like lectin 8 (human) |
Definition | A sialic acid-binding Ig-like lectin 8 that is encoded in the genome of human. |
Short Label | hSIGLEC8 |
Category | organism-gene |
Q9NYZ4 (SIGLEC8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y135 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y141 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S134 | N134 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |