Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYY8 / FAKD2_HUMAN
Protein Name FAST kinase domain-containing protein 2, mitochondrial precursor
Gene Name Name: FASTKD2
Synonyms:KIAA0971;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYY8
DAG View
PRO Name FAST kinase domain-containing protein 2, mitochondrial (human)
Definition A FAST kinase domain-containing protein 2, mitochondrial that is encoded in the genome of human.
Short Label hFASTKD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYY8 (FASTKD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S86 Phosphorylation PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus   UniProt 23186163
K132 Ubiquitination PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus   UniProt 23186163
K147 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
S160 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S167 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
C377 S-Nitrosylation dbSNO 19483679
S388 Phosphorylation PhosphoSitePlus
Y394 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
T687 Phosphorylation PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
K692 Ubiquitination PhosphoSitePlus
S708 Phosphorylation PhosphoSitePlus   UniProt 24275569
Site PTM Type PTM Enzyme Score Source PMID
S160 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S167 I167 Biomuta DOID:1324 / lung cancer [ tcga ]
S174 * Biomuta DOID:1324 / lung cancer [ tcga ]
S174 P174 Biomuta DOID:3571 / liver cancer [ tcga ]
K535 N535 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K692 Q692 Biomuta DOID:3070 / malignant glioma [ tcga ]
S708 T708 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S708 N708 Biomuta DOID:363 / uterine cancer [ tcga ]