iPTMnet Report for Q9NYU2 (UGGT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYU2 / UGGG1_HUMAN
Protein Name UDP-glucose:glycoprotein glucosyltransferase 1 precursor
Gene Name Name: UGGT1
Synonyms:GT,UGCGL1,UGGT,UGT1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYU2
DAG View
PRO Name UDP-glucose:glycoprotein glucosyltransferase 1 (human)
Definition A UDP-glucose:glycoprotein glucosyltransferase 1 that is encoded in the genome of human.
Short Label hUGGT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYU2 (UGGT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y96 Phosphorylation PhosphoSitePlus
Y98 Phosphorylation PhosphoSitePlus
Y99 Phosphorylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
Y244 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
T266 O-Glycosylation GlyGen 35008409, 35138101, 30397120, ...34725712, 30059200, 34019948, 32119511
N269 N-Glycosylation GlyGen 29741879, 24190977
N276 N-Glycosylation GlyGen 24190977
S337 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K378 Acetylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
Y449 Phosphorylation PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus
Y565 Phosphorylation PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus
Y684 Phosphorylation PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus
Y741 Phosphorylation PhosphoSitePlus
S748 Phosphorylation PhosphoSitePlus
Y779 Phosphorylation PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus
K930 Ubiquitination PhosphoSitePlus
S955 Phosphorylation PhosphoSitePlus
K959 Ubiquitination PhosphoSitePlus
Y966 Phosphorylation PhosphoSitePlus
R972 Methylation PhosphoSitePlus
S1026 Phosphorylation PhosphoSitePlus
K1034 Acetylation PhosphoSitePlus
R1038 Methylation PhosphoSitePlus
T1145 Phosphorylation PhosphoSitePlus
K1211 Acetylation IEDB 34357683
T1241 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S1277 Phosphorylation PhosphoSitePlus   UniProt 21406692
T1282 Phosphorylation PhosphoSitePlus
K1287 Ubiquitination PhosphoSitePlus
S1296 Phosphorylation PhosphoSitePlus
R1435 Methylation PhosphoSitePlus
Y1516 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y741 Phosphorylation HPRD 17287340
S748 Phosphorylation HPRD 17287340
S1296 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T253 A253 Biomuta DOID:363 / uterine cancer [ icgc ]
K362 N362 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y449 C449 Biomuta DOID:4159 / skin cancer [ cosmic ]
S748 F748 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y779 C779 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K959 E959 Biomuta DOID:1319 / brain cancer [ icgc ]
R972 T972 Biomuta DOID:1324 / lung cancer [ cosmic ]
R1038 C1038 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T1145 I1145 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1277 F1277 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1296 C1296 Biomuta DOID:5158 / pleural cancer [ cosmic ]