Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYQ8 / FAT2_HUMAN
Protein Name Protocadherin Fat 2 precursor
Gene Name Name: FAT2
Synonyms:CDHF8,KIAA0811,MEGF1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYQ8
DAG View
PRO Name protocadherin Fat 2 (human)
Definition A protocadherin Fat 2 that is encoded in the genome of human.
Short Label hFAT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYQ8 (FAT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y153 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
N568 N-Glycosylation GlyGen 23090970, 24190977
N627 N-Glycosylation GlyGen 23090970, 24190977
N655 N-Glycosylation GlyGen 23090970, 24190977
K804 Methylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
S885 Phosphorylation PhosphoSitePlus
Y889 Phosphorylation PhosphoSitePlus
N996 N-Glycosylation GlyGen 23090970, 24190977
Y1264 Phosphorylation PhosphoSitePlus
S1269 Phosphorylation PhosphoSitePlus
T1410 Phosphorylation PhosphoSitePlus
N1417 N-Glycosylation GlyGen 23090970, 24190977
S1516 Phosphorylation PhosphoSitePlus
Y1592 Phosphorylation HPRD   PhosphoSitePlus 20068231
S1704 Phosphorylation PhosphoSitePlus
Y1708 Phosphorylation PhosphoSitePlus
S1709 Phosphorylation PhosphoSitePlus
N1904 N-Glycosylation GlyGen 23090970, 24190977
S2155 Phosphorylation PhosphoSitePlus
N2183 N-Glycosylation GlyGen 23090970, 24190977
Y2205 Phosphorylation PhosphoSitePlus
Y2233 Phosphorylation PhosphoSitePlus
N2470 N-Glycosylation GlyGen 23090970, 24190977
N2547 N-Glycosylation GlyGen 23090970, 24190977
S2593 Phosphorylation PhosphoSitePlus
S2596 Phosphorylation PhosphoSitePlus
N2597 N-Glycosylation GlyGen 23090970, 24190977
S2599 Phosphorylation PhosphoSitePlus
Y2911 Phosphorylation HPRD 20068231
S2914 Phosphorylation HPRD   PhosphoSitePlus 20068231
S2919 Phosphorylation HPRD   PhosphoSitePlus 20068231
T2927 Phosphorylation HPRD   PhosphoSitePlus 20068231
K3086 Ubiquitination PhosphoSitePlus
N3125 N-Glycosylation GlyGen 23090970, 24190977
Y3274 Phosphorylation PhosphoSitePlus
Y3497 Phosphorylation PhosphoSitePlus
T3565 Phosphorylation PhosphoSitePlus
S3713 Phosphorylation PhosphoSitePlus
T3815 Phosphorylation PhosphoSitePlus
S3819 Phosphorylation PhosphoSitePlus
N3840 N-Glycosylation GlyGen 23090970, 24190977
S3870 Phosphorylation PhosphoSitePlus
N3873 N-Glycosylation GlyGen 23090970, 24190977
T3874 Phosphorylation PhosphoSitePlus
N3904 N-Glycosylation GlyGen   UniProt 16335952
T4036 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
Y4174 Phosphorylation PhosphoSitePlus
Y4223 Phosphorylation PhosphoSitePlus
S4303 Phosphorylation PhosphoSitePlus
Y4309 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S1704 C1704 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1709 F1709 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
N2183 I2183 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N2183 H2183 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2593 F2593 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S2593 P2593 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N2597 K2597 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y2911 * Biomuta DOID:1319 / brain cancer [ cosmic ]
T2927 I2927 Biomuta DOID:3571 / liver cancer [ cosmic ]
K3086 N3086 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T3565 A3565 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T3565 S3565 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S4303 N4303 Biomuta DOID:4159 / skin cancer [ cosmic ]