iPTMnet Report for Q9NYQ7 (CELSR3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYQ7 / CELR3_HUMAN
Protein Name Cadherin EGF LAG seven-pass G-type receptor 3 precursor
Gene Name Name: CELSR3
Synonyms:CDHF11,EGFL1,FMI1,KIAA0812,MEGF2;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYQ7
DAG View
PRO Name cadherin EGF LAG seven-pass G-type receptor 3 (human)
Definition A cadherin EGF LAG seven-pass G-type receptor 3 that is encoded in the genome of human.
Short Label hCELSR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYQ7 (CELSR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R53 Methylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
S278 Phosphorylation IEDB 35494241
S370 Phosphorylation PhosphoSitePlus
T534 Phosphorylation PhosphoSitePlus
S805 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T806 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y821 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y1198 Phosphorylation PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus
Y1208 Phosphorylation PhosphoSitePlus
S1209 Phosphorylation PhosphoSitePlus
T1580 Phosphorylation PhosphoSitePlus
K2062 Ubiquitination PhosphoSitePlus
K2131 Ubiquitination PhosphoSitePlus
K2143 Ubiquitination PhosphoSitePlus
T2149 Phosphorylation PhosphoSitePlus
K2197 Ubiquitination PhosphoSitePlus
K2206 Ubiquitination PhosphoSitePlus
K2207 Ubiquitination PhosphoSitePlus
K2477 Ubiquitination PhosphoSitePlus
S2508 Phosphorylation PhosphoSitePlus
K2790 Ubiquitination PhosphoSitePlus
S2826 Phosphorylation PhosphoSitePlus
S2899 Phosphorylation PhosphoSitePlus
Y3017 Phosphorylation PhosphoSitePlus
Y3051 Phosphorylation PhosphoSitePlus
T3056 Phosphorylation PhosphoSitePlus
S3058 Phosphorylation PhosphoSitePlus
S3060 Phosphorylation PhosphoSitePlus
S3064 O-Glycosylation GlyGen 29237092, 35254053
S3068 Phosphorylation PhosphoSitePlus
S3081 Phosphorylation PhosphoSitePlus
S3140 Phosphorylation PhosphoSitePlus
S3175 Phosphorylation PhosphoSitePlus
S3209 Phosphorylation PhosphoSitePlus
S3300 O-Glycosylation GlyGen 29237092, 35254053
S3308 O-Glycosylation GlyGen 29237092, 35254053
Site PTM Type PTM Enzyme Score Source PMID
S805 Phosphorylation HPRD 18669648
T806 Phosphorylation HPRD 18669648
Y821 Phosphorylation HPRD 18669648
S3060 Phosphorylation HPRD 18077418


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R53 M53 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S805 R805 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S805 T805 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
S1209 F1209 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1209 Y1209 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K2062 E2062 Biomuta DOID:363 / uterine cancer [ icgc ]
T3056 M3056 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S3209 N3209 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]