iPTMnet Report for Q9NYQ6 (CELSR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYQ6 / CELR1_HUMAN
Protein Name Cadherin EGF LAG seven-pass G-type receptor 1 precursor
Gene Name Name: CELSR1
Synonyms:CDHF9,FMI2;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYQ6
DAG View
PRO Name cadherin EGF LAG seven-pass G-type receptor 1 (human)
Definition A cadherin EGF LAG seven-pass G-type receptor 1 that is encoded in the genome of human.
Short Label hCELSR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYQ6 (CELSR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S213 O-Glycosylation GlyGen 30459171
S215 O-Glycosylation GlyGen 30459171
S281 Phosphorylation PhosphoSitePlus
Y282 Phosphorylation PhosphoSitePlus
Y283 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
N403 N-Glycosylation GlyGen 29741879
S616 Phosphorylation PhosphoSitePlus
N1287 N-Glycosylation GlyGen 29741879
S1326 Phosphorylation PhosphoSitePlus
T1334 Phosphorylation PhosphoSitePlus
N1576 N-Glycosylation GlyGen 23090970, 24190977
N1623 N-Glycosylation GlyGen 29741879
S1625 O-Glycosylation GlyGen 35289036
N1639 N-Glycosylation GlyGen 24190977
N1640 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N1979 N-Glycosylation GlyGen 23090970, 29741879, 24190977
T1999 Phosphorylation IEDB 35494241
N2122 N-Glycosylation GlyGen 23090970, 29741879, 24190977
R2229 Methylation PhosphoSitePlus
T2306 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T2307 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T2310 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T2311 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S2491 Phosphorylation PhosphoSitePlus
K2713 Ubiquitination PhosphoSitePlus
K2720 Ubiquitination PhosphoSitePlus
S2726 Phosphorylation PhosphoSitePlus
S2737 Phosphorylation PhosphoSitePlus
T2742 Phosphorylation PhosphoSitePlus
T2743 Phosphorylation PhosphoSitePlus
S2761 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2764 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S2784 Phosphorylation PhosphoSitePlus
S2871 Phosphorylation PhosphoSitePlus
S2889 Phosphorylation PhosphoSitePlus
S2960 Phosphorylation PhosphoSitePlus
S2971 Phosphorylation PhosphoSitePlus
S2982 Phosphorylation PhosphoSitePlus
S3009 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2761 Phosphorylation HPRD 18669648
S2764 Phosphorylation HPRD 18669648
S2867 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S215 L215 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S356 L356 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S616 N616 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1625 P1625 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R2229 C2229 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T2307 I2307 Biomuta DOID:1612 / breast cancer [ cosmic ]
K2720 N2720 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2971 F2971 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S2982 N2982 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3009 F3009 Biomuta DOID:4159 / skin cancer [ cosmic ]