iPTMnet Report for Q9NYL9 (TMOD3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYL9 / TMOD3_HUMAN
Protein Name Tropomodulin-3
Gene Name Name: TMOD3
Organism Homo sapiens (Human)

PRO ID PR:Q9NYL9
DAG View
PRO Name tropomodulin-3 (human)
Definition A tropomodulin-3 that is encoded in the genome of human.
Short Label hTMOD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYL9 (TMOD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y12 Phosphorylation PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
S25 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 19664994, 18452278, 19651622, 17322306, 18669648, 24275569, 20166139, 19415658, 20068231
T27 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
K53 Ubiquitination PhosphoSitePlus
S59 Phosphorylation HPRD   PhosphoSitePlus 20068231
S71 Phosphorylation PhosphoSitePlus   RLIMS-P 25575350, 26280982
Y72 Phosphorylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K96 Sumoylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
K169 Sumoylation PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K172 Acetylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K209 Sumoylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
R294 Methylation PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
K317 Sumoylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S25 P25 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y72 S72 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S155 I155 Biomuta DOID:3571 / liver cancer [ icgc ]
K191 N191 Biomuta DOID:363 / uterine cancer [ tcga ]
K191 Q191 Biomuta DOID:1909 / melanoma [ cosmic ]
K221 E221 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K344 R344 Biomuta DOID:1324 / lung cancer [ cosmic ]