iPTMnet Report for Q9NYL5 (CYP39A1)
Protein Information
| UniProt AC / UniProt ID | Q9NYL5 / CP39A_HUMAN |
| Protein Name | 24-hydroxycholesterol 7-alpha-hydroxylase precursor |
| Gene Name | Name: CYP39A1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NYL5 |
| PRO Name | 24-hydroxycholesterol 7-alpha-hydroxylase (human) |
| Definition | A cytochrome P450 39A1 that is encoded in the genome of human. |
| Short Label | hCYP39A1 |
| Category | organism-gene |
DAG ViewQ9NYL5 (CYP39A1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y102 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T245 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K316 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T345 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S361 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S368 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K386 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S361 | P361 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K386 | E386 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
