iPTMnet Report for Q9NYK5 (MRPL39)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYK5 / RM39_HUMAN
Protein Name Large ribosomal subunit protein mL39
Gene Name Name: MRPL39
Synonyms:C21orf92,MRPL5,RPML5;ORFNames:MSTP003,PRED22;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYK5
DAG View
PRO Name 39S ribosomal protein L39, mitochondrial (human)
Definition A 39S ribosomal protein L39, mitochondrial that is encoded in the genome of human.
Short Label hMRPL39
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYK5 (MRPL39) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus
K72 Acetylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
Y99 Phosphorylation PhosphoSitePlus
K126 Acetylation PhosphoSitePlus   UniProt 19608861
K131 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
R200 Methylation PhosphoSitePlus
K204 Acetylation PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K253 Methylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
T332 Phosphorylation PhosphoSitePlus
C335 S-Nitrosylation dbSNO 26338901


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T59 P59 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T59 N59 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K196 Q196 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R200 C200 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
R200 H200 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R200 L200 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K315 T315 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]