iPTMnet Report for Q9NYD6 (HOXC10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYD6 / HXC10_HUMAN
Protein Name Homeobox protein Hox-C10
Gene Name Name: HOXC10
Synonyms:HOX3I;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYD6
DAG View
PRO Name homeobox protein Hox-C10 (human)
Definition A homeobox protein Hox-C10 that is encoded in the genome of human.
Short Label hHOXC10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYD6 (HOXC10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T8 O-Glycosylation GlyGen 23301498, 30379171, 30059200, ...30620550, 35289036, 35254053
T8 Phosphorylation PhosphoSitePlus   UniProt 23186163
S11 O-Glycosylation GlyGen 23301498, 34846842, 30379171, ...30059200, 35254053, 35289036, 30620550
K55 Ubiquitination PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
S189 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
K195 Sumoylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus
K203 Sumoylation PhosphoSitePlus
S204 O-Glycosylation GlyGen 23301498, 30379171, 30059200, ...30620550, 35289036, 35254053
S204 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
T208 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
K215 Sumoylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
S226 Phosphorylation HPRD   PhosphoSitePlus 19651622
S228 Phosphorylation HPRD   PhosphoSitePlus 19651622
S230 Phosphorylation PhosphoSitePlus
K254 Sumoylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
S337 Phosphorylation HPRD   PhosphoSitePlus 18491316
T342 Phosphorylation HPRD   PhosphoSitePlus 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 A11 Biomuta DOID:363 / uterine cancer [ icgc ]
K55 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K121 E121 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T161 M161 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S189 L189 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S204 F204 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S206 R206 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K215 N215 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K254 E254 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K254 N254 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K266 N266 Biomuta DOID:363 / uterine cancer [ icgc ]